CD2AP

Gene Symbol CD2AP
Entrez Gene 23607
Alt Symbol CMS
Species Human
Gene Type protein-coding
Description CD2-associated protein
Other Description Cas ligand with multiple Src homology 3 (SH3) domains|adapter protein CMS|cas ligand with multiple SH3 domains
Swissprots Q9UG97 Q9Y5K6 Q5VYA3 A6NL34
Accessions EAX04319 Q9Y5K6 AF146277 AAD34595 AF164377 AAF80495 AJ420469 AL050105 CAB43274 BC069444 AAH69444 BU679191 DA040834 XM_005248976 XP_005249033 XM_005248977 XP_005249034 XM_011514449 XP_011512751 NM_012120 NP_036252
Function Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T- cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. {ECO:0000269|PubMed:15800069}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Colocalizes with F-actin and BCAR1/p130Cas in membrane ruffles. Located at podocyte slit diaphragm between podocyte foot processes (By similarity). During late anaphase and telophase, concentrates in the vicinity of the midzone microtubules and in the midbody in late telophase. {ECO:0000250, ECO:0000269|PubMed:15800069}.
Tissue Specificity Widely expressed in fetal and adult tissues.
Top Pathways Bacterial invasion of epithelial cells

CD2-associated protein (CD2AP), Human, ELISA Kit - CSB-EL004914HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

CD2-associated protein (CD2AP), Human, ELISA Kit - E01C1474 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

CD2 associated protein (CD2AP), ELISA Kit - MBS7207339 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein, ELISA Kit - MBS947714 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human CD2AP is typically less than 4.7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 18.75 pg/ml -1200 pg/ml.

CD2-associated protein (CD2AP), ELISA Kit - MBS7245598 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7216160 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7251283 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7211618 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7219561 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7249032 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7241357 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7251087 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7230641 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7250881 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CD2-associated protein (CD2AP), ELISA Kit - MBS7211492 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human CD2-associated protein(CD2AP) ELISA kit - CSB-EL004914HU from Cusabio

Category ELISA Kit
Sensitivity 4.7 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human CD2AP ELISA Kit - E007343 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human CD2AP is typically less than 4.7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mea

CD2AP ELISA Kit (Human) (OKCA01150) - OKCA01150 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 4.7 pg/mL
Range 18.75 - 1,200 pg/mL

Human CD2AP ELISA Kit - orb404119 from Biorbyt

Category ELISA Kit
Sensitivity 4.7 pg/ml
Range 18.75 pg/ml-1200 pg/ml
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