TIAM2

Gene Symbol	TIAM2
Entrez Gene	26230
Alt Symbol	STEF, TIAM-2
Species	Human
Gene Type	protein-coding
Description	T-cell lymphoma invasion and metastasis 2
Other Description	SIF and TIAM1-like exchange factor|T-lymphoma invasion and metastasis-inducing protein 2
Swissprots	B2RP56 Q9UKV9 Q9UFG6 Q6ZUP9 Q8IVF5 Q9UKW0 C9JZV2 Q6NXN9
Accessions	EAW47692 EAW47693 Q8IVF5 AF120323 AAF05900 AF120324 AAF05901 AF195656 AAF03902 AK123859 BAG53973 AK125459 BAC86170 AK299723 BAH13110 AK302860 BAH13824 AL122086 CAB59259 BC022469 BC066979 AAH66979 BC137275 AAI37276 BP199501 NM_001010927 NP_001010927 NM_012454 NP_036586
Function	Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA. {ECO:0000250, ECO:0000269|PubMed:10512681}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell projection, lamellipodium {ECO:0000250}. Cell projection, filopodium {ECO:0000250}. Cell projection, growth cone. Note=Localizes to the plasma membrane in neurites. {ECO:0000250}.
Tissue Specificity	Expressed in the occipital, frontal and temporal lobes, cerebellum, putamen and testis. {ECO:0000269|PubMed:10512681}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TIAM2 full length protein - ab132621 from Abcam Category Protein Source Wheat germ Species Human

TIAM2 peptide - ab107103 from Abcam Category Peptide

TIAM2 Antibody Blocking Peptide - LS-E2564 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TIAM2 Antibody Blocking Peptide - LS-E27550 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TIAM2 Antibody Blocking Peptide - LS-E27551 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TIAM2 Protein - H00026230-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TIAM2 Recombinant Protein - H00026230-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TIAM2-Antibody-N-term-Blocking-peptide - BP13610a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TIAM2 Immunizing peptide - orb66259 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

TIAM2 Peptide - AC21-2372-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TIAM2 Peptide - AC21-2373-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TIAM2 - H00026230-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TIAM2 - H00026230-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TIAM2 - H00026230-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TIAM2 - H00026230-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TIAM2 Peptide - 42-833P from ProSci Category Peptide

TIAM2 Peptide - 42-987P from ProSci Category Peptide

Recombinant Human TIAM2, His-tagged - TIAM2-30624TH from Creative Biomart Category Protein Source E. coli

Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2(TIAM2) ,partial - CSB-YP818235HU CSB-EP818235HU CSB-BP818235HU CSB-MP818235HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TIAM2 (transcript variant 2) - TP313556 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

T-lymphoma invasion and metastasis-inducing protein 2 (TIAM2), partial, Recombinant Protein - MBS1410258 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TIAM2, Peptide - MBS427553 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog

TIAM2, Peptide - MBS428244 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Dog

TIAM2 Protein - NBP1-80714PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TIAM2 Recombinant Protein Antigen - NBP1-80713PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Search more