Gene Symbol | CITED2 |
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Entrez Gene | 10370 |
Alt Symbol | ASD8, MRG-1, MRG1, P35SRJ, VSD2 |
Species | Human |
Gene Type | protein-coding |
Description | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
Other Description | MSG-related protein 1|MSG1-related gene 1|cbp/p300-interacting transactivator 2|melanocyte-specific gene 1-related gene 1 |
Swissprots | Q5VTF4 Q99967 O95426 |
Accessions | AAF01263 AAF01264 ADL14510 EAW47891 EAW47892 EAW47893 EAW47894 EAW47895 Q99967 AA400897 AA767624 AF109161 AAD10055 AI087283 BC004377 AAH04377 BG900380 BI763038 BM763150 BM851650 CF126189 DQ893296 ABM84222 DQ896731 ABM87730 U65093 AAC51114 NM_001168388 NP_001161860 NM_001168389 NP_001161861 NM_006079 NP_006070 |
Function | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator- activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left- right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral pla |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12586840, ECO:0000269|PubMed:8901575, ECO:0000269|PubMed:9887100}. Note=Colocalizes with EP300 in dot-like structures. |
Human CITED2 full length protein - ab87363 from Abcam
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Human CITED2 peptide - ab22995 from Abcam
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Human CITED2 protein fragment - ab80152 from Abcam
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CITED2 Antibody Blocking Peptide - LS-E88 from LifeSpan Bioscience
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CITED2 Antibody Blocking Peptide - LS-E31348 from LifeSpan Bioscience
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CITED2 Antibody Blocking Peptide - LS-E26023 from LifeSpan Bioscience
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CITED2 Antibody Blocking Peptide - LS-E12723 from LifeSpan Bioscience
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Cited-2 Recombinant Protein - H00010370-P01 from Novus Biologicals
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Recombinant Human Cited-2 Protein - NBC1-28611 from Novus Biologicals
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CITED2-Antibody-C-term-Blocking-peptide - BP10174b from Abgent, a WuXi AppTec company
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CITED2 Protein (OPPA02234) - OPPA02234 from Aviva Systems Biology
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Human Cbp/p300-Interacting Transactivator 2 protein - orb81033 from Biorbyt
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CITED2 protein (His tag) - 80R-1155 from Fitzgerald
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CITED2 Peptide - AC21-0851-P from Abcore
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CITED2 (1-270, His-tag) - AR09207PU-L from Acris Antibodies
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CITED2 (1-270, His-tag) - AR09207PU-N from Acris Antibodies
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CITED2 - H00010370-P01-10 from Acris Antibodies
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CITED2 - H00010370-P01-25 from Acris Antibodies
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Cbp/p300-Interacting Transactivator 2, Human Recombinant - 228-10237-1 from RayBiotech
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Recombinant Human CITED2 - 228-10237-2 from RayBiotech
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Recombinant Human CITED2 - 228-10237-3 from RayBiotech
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CITED2, 1- 270 aa, Human, His-tagged, Recombinant, E.coli - 01-2087 from ARP American Research Products
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CITED2 Peptide - 45-404P from ProSci
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CITED2 Peptide - 7067P from ProSci
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CITED2 fusion protein - ag7078 from Proteintech Group
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