CITED2

Gene Symbol CITED2
Entrez Gene 10370
Alt Symbol ASD8, MRG-1, MRG1, P35SRJ, VSD2
Species Human
Gene Type protein-coding
Description Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Other Description MSG-related protein 1|MSG1-related gene 1|cbp/p300-interacting transactivator 2|melanocyte-specific gene 1-related gene 1
Swissprots Q5VTF4 Q99967 O95426
Accessions AAF01263 AAF01264 ADL14510 EAW47891 EAW47892 EAW47893 EAW47894 EAW47895 Q99967 AA400897 AA767624 AF109161 AAD10055 AI087283 BC004377 AAH04377 BG900380 BI763038 BM763150 BM851650 CF126189 DQ893296 ABM84222 DQ896731 ABM87730 U65093 AAC51114 NM_001168388 NP_001161860 NM_001168389 NP_001161861 NM_006079 NP_006070
Function Transcriptional coactivator of the p300/CBP-mediated trancription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Stimulates the peroxisome proliferator- activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimulating transcription activation of SRY. Plays a role in controlling left- right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral pla
Subcellular Location Nucleus {ECO:0000269|PubMed:12586840, ECO:0000269|PubMed:8901575, ECO:0000269|PubMed:9887100}. Note=Colocalizes with EP300 in dot-like structures.

MRG1 (N-15) - sc-9669 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MRG1 (N-15): sc-9669. Western blot analysis of MRG1 expression in IMR-32 nuclear extract.

MRG1 (S-17) - sc-9670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MRG1 (JA22) - sc-21795 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MRG1 (JA22): sc-21795. Western blot analysis of MRG1 expression in IMR-32 nuclear extract.

MRG1 (H-220) - sc-25375 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MRG1 (H-220): sc-25375. Immunofluorescense staining of methanol-fixed HeLa cells showing weak nuclear (A) and strong nuclear localization after IL-6 induction (B).

Anti-CITED2 antibody - ab99335 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CITED2 antibody (ab99335) at 1 µg/mlLane 1 : Caco 2 (Human colonic carcinoma cell line) Whole Cell LysateLane 2 : SW13 (Human adrenal adenocarcinoma) Whole Cell LysateLane 3 : Saos 2 (Human epithelial-like osteosarcoma cell line) Whole Cell LysateLane 4 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 5 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CITED2 antibody - ab76037 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CITED2 antibody (ab76037) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µgSecondaryHRP-conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CITED2 antibody - ab184145 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemical analysis of HeLa cells fixed in 4% paraformaldehyde at room temperature for 15 min labeling CITED2 with ab184145 at 1/1000 (green) and Hoechst 33342 (blue).

Anti-CITED2 antibody - ab172539 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CITED2 antibody (ab172539) at 1 µg/mlLane 1 : CITED2 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-CITED2 antibody [EPR3416(2)] - ab108345 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3416(2)
All lanes : Anti-CITED2 antibody [EPR3416(2)] (ab108345) at 1/1000 dilutionLane 1 : Saos 2 cell lysateLane 2 : U937 cell lysateLane 3 : HeLa cell lysateLysates/proteins at 10 µg per lane.

Anti-CITED2 antibody [JA22] - ab5155 from Abcam

Host Mouse
Clonality Monoclonal
Clone JA22

Anti-CITED2 antibody - N-terminal - ab189946 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 :  Anti-CITED2 antibody - N-terminal (ab189946) at 1 µg/mlLane 2 :  Anti-CITED2 antibody - N-terminal (ab189946) at 2 µg/mlLane 1 : Jurkat cell lysateLane 2 : Jurkat cell lysate

Anti-CITED2 Antibody (Internal) - LS-C47568 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CITED2 Antibody (C-Terminus) - LS-C79336 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-CITED2 Antibody (aa1-269, clone 11n47) - LS-C184204 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 11n47

Anti-CITED2 Antibody (aa207-234, APC) - LS-C213313 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (aa207-234, FITC) - LS-C213315 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (aa207-234, Biotin) - LS-C213314 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (aa207-234, AP) - LS-C213312 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (aa207-234, Azide-free, HRP) - LS-C213317 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (aa55-104) - LS-C80129 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal brain lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CITED2 Antibody (aa207-234, PE) - LS-C213318 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (aa207-234) - LS-C320405 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CITED2 Antibody (N-Terminus) - LS-C80228 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CITED2 Antibody (Internal, clone EPR3416(2)) - LS-C138092 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3416(2)
Western blot analysis on (A) Saos-2, (B) U937, and (C) HeLa cell lysates using anti-CITED2 antibody.

Anti-CITED2 Antibody (aa207-234) - LS-C168786 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CITED2 Antibody western blot of mouse NIH-3T3 cell line lysates (15 ug/lane). The CITED2 antibody detected CITED2 protein (arrow).
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