Gene Symbol | ITPKC |
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Entrez Gene | 80271 |
Alt Symbol | IP3-3KC, IP3KC |
Species | Human |
Gene Type | protein-coding |
Description | inositol-trisphosphate 3-kinase C |
Other Description | IP3 3-kinase C|IP3K C|InsP 3 kinase C|inositol 1,4,5-trisphosphate 3-kinase C|insP 3-kinase C |
Swissprots | Q96DU7 Q9UE25 Q9Y475 |
Accessions | EAW56992 EAW56993 Q96DU7 AJ290975 CAC40815 AK024596 BC026903 BC060788 AAH60788 D38169 BAA22524 Y11999 CAA72728 XM_006723404 XP_006723467 XR_243961 NM_025194 NP_079470 |
Function | Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12747803}. Cytoplasm {ECO:0000269|PubMed:12747803}. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity. |
Tissue Specificity | Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain. {ECO:0000269|PubMed:11085927}. |
Top Pathways | Calcium signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system |
IP3KC (C-14) - sc-11221 from Santa Cruz Biotechnology
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IP3KC (N-20) - sc-11218 from Santa Cruz Biotechnology
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Anti-IP3KC antibody - ab188007 from Abcam
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Anti-IP3KC antibody - ab65025 from Abcam
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Anti-IP3KC antibody - ab92283 from Abcam
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Anti-ITPKC Antibody (aa89-117, APC) - LS-C260581 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa89-117, AP) - LS-C260582 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa89-117, Biotin) - LS-C260583 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa89-117, FITC) - LS-C260584 from LifeSpan Bioscience
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Anti-ITPKC Antibody - LS-C308556 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa89-117, Azide-free, HRP) - LS-C260585 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa89-117, PE) - LS-C260586 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa96-125) - LS-C322313 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa221-270) - LS-C119207 from LifeSpan Bioscience
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Anti-ITPKC Antibody (Internal) - LS-C155229 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa105-119) - LS-C112773 from LifeSpan Bioscience
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Anti-ITPKC Antibody (aa89-117) - LS-C165339 from LifeSpan Bioscience
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IP3KC Antibody - NBP1-36962 from Novus Biologicals
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IP3KC Antibody - NBP2-16982 from Novus Biologicals
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IP3KC Antibody - NBP1-55699 from Novus Biologicals
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IP3KC Antibody - H00080271-B01P from Novus Biologicals
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IP3KC Antibody - H00080271-B01 from Novus Biologicals
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IP3KC Antibody - H00080271-A01 from Novus Biologicals
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Anti-IP3KC antibody produced in rabbit - SAB4503202 from Sigma-Aldrich
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Anti-ITPKC antibody produced in mouse - SAB1408021 from Sigma-Aldrich
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