ITPKC

Gene Symbol ITPKC
Entrez Gene 80271
Alt Symbol IP3-3KC, IP3KC
Species Human
Gene Type protein-coding
Description inositol-trisphosphate 3-kinase C
Other Description IP3 3-kinase C|IP3K C|InsP 3 kinase C|inositol 1,4,5-trisphosphate 3-kinase C|insP 3-kinase C
Swissprots Q96DU7 Q9UE25 Q9Y475
Accessions EAW56992 EAW56993 Q96DU7 AJ290975 CAC40815 AK024596 BC026903 BC060788 AAH60788 D38169 BAA22524 Y11999 CAA72728 XM_006723404 XP_006723467 XR_243961 NM_025194 NP_079470
Function Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12747803}. Cytoplasm {ECO:0000269|PubMed:12747803}. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
Tissue Specificity Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain. {ECO:0000269|PubMed:11085927}.
Top Pathways Calcium signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system

IP3KC (C-14) - sc-11221 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IP3KC (N-20) - sc-11218 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IP3KC antibody - ab188007 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IP3KC antibody (ab188007) at 1/500 dilutionLane 1 : RT4 cell lysateLane 2 : U-251MG sp cell lysate

Anti-IP3KC antibody - ab65025 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IP3KC antibody (ab65025) at 1/500 dilutionLane 1 : HT29 cell extractLane 2 : HT29 cell extract with immunising peptide

Anti-IP3KC antibody - ab92283 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-IP3KC antibody (ab92283) at 1 µg/ml + Human Pancreas lysate at 35 µgdeveloped using the ECL technique

Anti-ITPKC Antibody (aa89-117, APC) - LS-C260581 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody (aa89-117, AP) - LS-C260582 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody (aa89-117, Biotin) - LS-C260583 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody (aa89-117, FITC) - LS-C260584 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody - LS-C308556 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ITPKC Antibody (aa89-117, Azide-free, HRP) - LS-C260585 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody (aa89-117, PE) - LS-C260586 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody (aa96-125) - LS-C322313 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ITPKC Antibody (aa221-270) - LS-C119207 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HT-29 cells, using IP3KC Antibody. The lane on the right is treated with the synthesized peptide.

Anti-ITPKC Antibody (Internal) - LS-C155229 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE ITPKC / IP3KC antibody diluted at 1:1000

Anti-ITPKC Antibody (aa105-119) - LS-C112773 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ITPKC antibody (1 ug/ml) staining of Human Pancreas lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-ITPKC Antibody (aa89-117) - LS-C165339 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ITPKC Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

IP3KC Antibody - NBP1-36962 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: IP3KC Antibody [NBP1-36962] - taining of Human Pancreas (A), Heart (B) and Skeletal Muscle (C) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IP3KC Antibody - NBP2-16982 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IP3KC Antibody - NBP1-55699 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: IP3KC Antibody [NBP1-55699] - Analysis of extracts from HT-29 cells, using IP3KC Antibody. The lane on the right is treated with the synthesized peptide.

IP3KC Antibody - H00080271-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: IP3KC Antibody [H00080271-B01P] - Analysis of ITPKC expression in transfected 293T cell line by ITPKC polyclonal antibody.  Lane1:ITPKC transfected lysate(75.13 KDa). Lane2:Non-transfected lysate.

IP3KC Antibody - H00080271-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: IP3KC Antibody [H00080271-B01] - analysis of ITPKC expression in transfected 293T cell line by ITPKC MaxPab polyclonal antibody (B01). Lane1: ITPKC transfected lysate (75.20 KDa). Lane2: Non-transfected lysate.

IP3KC Antibody - H00080271-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-IP3KC antibody produced in rabbit - SAB4503202 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IP3KC: <B>Cat. No. SAB4503202</B>: Immunoblotting analysis of extracts from HT-29 cells, using Anti-IP3KC antibody. The lane on the left was treated with the Anti-IP3KC antibody. The lane on the right (negative control) was treated with both Anti-IP3KC antibody and the synthesized immunogen peptide.

Anti-ITPKC antibody produced in mouse - SAB1408021 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ITPKC: <B>Cat. No. SAB1408021</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~75.1 kDa using ITPKC transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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