| Gene Symbol |
ITPKC
|
| Entrez Gene |
80271
|
| Alt Symbol |
IP3-3KC, IP3KC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inositol-trisphosphate 3-kinase C
|
| Other Description |
IP3 3-kinase C|IP3K C|InsP 3 kinase C|inositol 1,4,5-trisphosphate 3-kinase C|insP 3-kinase C
|
| Swissprots |
Q96DU7 Q9UE25 Q9Y475
|
| Accessions |
EAW56992 EAW56993 Q96DU7 AJ290975 CAC40815 AK024596 BC026903 BC060788 AAH60788 D38169 BAA22524 Y11999 CAA72728 XM_006723404 XP_006723467 XR_243961 NM_025194 NP_079470
|
| Function |
Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:12747803}. Cytoplasm {ECO:0000269|PubMed:12747803}. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
|
| Tissue Specificity |
Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain. {ECO:0000269|PubMed:11085927}.
|
| Top Pathways |
Calcium signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system
|