Gene Symbol | ITPKC |
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Entrez Gene | 80271 |
Alt Symbol | IP3-3KC, IP3KC |
Species | Human |
Gene Type | protein-coding |
Description | inositol-trisphosphate 3-kinase C |
Other Description | IP3 3-kinase C|IP3K C|InsP 3 kinase C|inositol 1,4,5-trisphosphate 3-kinase C|insP 3-kinase C |
Swissprots | Q96DU7 Q9UE25 Q9Y475 |
Accessions | EAW56992 EAW56993 Q96DU7 AJ290975 CAC40815 AK024596 BC026903 BC060788 AAH60788 D38169 BAA22524 Y11999 CAA72728 XM_006723404 XP_006723467 XR_243961 NM_025194 NP_079470 |
Function | Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:12747803}. Cytoplasm {ECO:0000269|PubMed:12747803}. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity. |
Tissue Specificity | Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain. {ECO:0000269|PubMed:11085927}. |
Top Pathways | Calcium signaling pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system |
Human IP3KC full length protein - ab164240 from Abcam
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Human IP3KC protein fragment - ab164241 from Abcam
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ITPKC Antibody Blocking Peptide - LS-E26921 from LifeSpan Bioscience
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ITPKC Antibody Blocking Peptide - LS-E10069 from LifeSpan Bioscience
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Recombinant Human IP3KC Protein - H00080271-Q01 from Novus Biologicals
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Recombinant Human IP3KC Protein - H00080271-P01 from Novus Biologicals
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ITPKC-Antibody-N-term-Blocking-Peptide - BP9326a from Abgent, a WuXi AppTec company
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IP3KC blocking peptide - GTX47572-PEP from GeneTex
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ITPKC Immunizing peptide - orb55043 from Biorbyt
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IP3KC Peptide - AC21-1752-P from Abcore
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IP3 3-kinase C / ITPKC - H00080271-P01-10 from Acris Antibodies
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IP3 3-kinase C / ITPKC - H00080271-P01-25 from Acris Antibodies
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IP3 3-kinase C / ITPKC - H00080271-Q01-10 from Acris Antibodies
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IP3 3-kinase C / ITPKC - H00080271-Q01-25 from Acris Antibodies
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ITPKC Peptide - 42-050P from ProSci
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ITPKC fusion protein - Ag5583 from Proteintech Group
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Recombinant Human ITPKC, GST-tagged - ITPKC-192H from Creative Biomart
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ITPKC Blocking Peptide - CBP3440 from Cohesion Biosciences
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Recombinant Human Inositol-trisphosphate 3-kinase C(ITPKC) - CSB-YP839309HU CSB-EP839309HU CSB-BP839309HU CSB-MP839309HU from Cusabio
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IP3 3-kinase C / ITPKC - TP309200 from Acris Antibodies
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IP3KC, Peptide - MBS427003 from MyBioSource
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ITPKC Blocking Peptide - abx162302 from Abbexa
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IP3KC Recombinant Protein Antigen - NBP2-49068PEP from Novus Biologicals
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ITPKC Peptide, Human - M34GP07829H from Creative Peptides
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IP3KC Recombinant Protein Antigen - NBP2-48975PEP from Novus Biologicals
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