PRC1

Gene Symbol	PRC1
Entrez Gene	9055
Alt Symbol	ASE1
Species	Human
Gene Type	protein-coding
Description	protein regulator of cytokinesis 1
Other Description	anaphase spindle elongation 1 homolog|protein regulating cytokinesis 1
Swissprots	B4DLR1 H9KV59 O43663 Q9BSB6 A6NC44
Accessions	CAM84944 CAM84945 CAM84946 EAX02134 EAX02135 EAX02136 EAX02137 EAX02138 O43663 AF044588 AAC02688 AK297117 BAG59623 AK304094 BAG65000 AK312600 BC003138 AAH03138 BC005140 AAH05140 BG773441 BG823292 BU634391 BX457401 BX647317 DA655494 DQ892933 ABM83859 DQ896182 ABM87181 DW423775 XM_005254987 XP_005255044 XM_006720759 XP_006720822 XM_006720760 XP_006720823 XM_011522187 XP_011520489 XM_011522188 XP_011520490 XM_011522189 XP_011520491 XM_011522190 XP_011520492 XM_011522191 XP_011520493 XM_011522192 XP_011520494 NM_001267580 NP_001254509 NM_003981 NP_003972 NM_199413 NP_955445 NM_199414
Function	Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. {ECO:0000269|PubMed:12082078, ECO:0000269|PubMed:15297875, ECO:0000269|PubMed:15625105, ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:19468300, ECO:0000269|PubMed:20691902, ECO:0000269|PubMed:9885575}.
Subcellular Location	Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PRC1 full length protein - ab132234 from Abcam Category Protein Source Wheat germ Species Human

PRC1 Antibody Blocking Peptide - LS-E31265 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human PRC1 Protein - H00009055-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human PRC1 protein (His Tag) - orb139514 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source Baculovirus-Insect Cells Species Human

PRC1 - H00009055-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PRC1 - H00009055-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PRC1 (Center) Control Peptide - AP55431CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PRC1 Peptide - 6821P from ProSci Category Peptide Species Human

PRC1 fusion protein - ag5907 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

PRC1 fusion protein - Ag8028 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PRC1 fusion protein - Ag0163 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Human PRC1 Protein (His Tag) - 13280-H07B-20 from Sino Biological Category Protein Prices $138.00, $298.00 Sizes 20 µg, 50 µg Source Baculovirus-Insect Cells Species Human

Recombinant Human Protein regulator of cytokinesis 1(PRC1) - CSB-YP018633HU CSB-EP018633HU CSB-BP018633HU CSB-MP018633HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PRC1 (451-620) - sc-4268 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

PRC1 Protein - abx163816 from Abbexa Category Protein Species Human

PRC1 (transcript variant 1) - TP301141 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human PRC1 Protein (His tag) - PKSH030666 from Elabscience Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human PRC1 Protein, His-tagged - PRC1-527H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

PRC1 Recombinant Protein Antigen - NBP1-88856PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PRC1-Antibody-Center-E186-Blocking-Peptide - BP7317d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRC1-Antibody-Center-H439-Blocking-Peptide - BP7317c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRC1 Peptide, Human - M34GP12341H from Creative Peptides Category Peptide Source Synthetic. Species Human

PRC1, Recombinant Protein - MBS2545340 from MyBioSource Category Protein Prices $375.00, $775.00 Sizes 20 µg, 50 µg Source Baculovirus-Insect Cells

Protein regulator of cytokinesis 1 (PRC1), Recombinant Protein - MBS1083777 from MyBioSource Category Protein Prices $1,415.00, $1,415.00, $1,645.00, $1,645.00, $2,390.00, $2,390.00, $2,835.00, $2,835.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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