PRC1

Gene Symbol PRC1
Entrez Gene 9055
Alt Symbol ASE1
Species Human
Gene Type protein-coding
Description protein regulator of cytokinesis 1
Other Description anaphase spindle elongation 1 homolog|protein regulating cytokinesis 1
Swissprots B4DLR1 H9KV59 O43663 Q9BSB6 A6NC44
Accessions CAM84944 CAM84945 CAM84946 EAX02134 EAX02135 EAX02136 EAX02137 EAX02138 O43663 AF044588 AAC02688 AK297117 BAG59623 AK304094 BAG65000 AK312600 BC003138 AAH03138 BC005140 AAH05140 BG773441 BG823292 BU634391 BX457401 BX647317 DA655494 DQ892933 ABM83859 DQ896182 ABM87181 DW423775 XM_005254987 XP_005255044 XM_006720759 XP_006720822 XM_006720760 XP_006720823 XM_011522187 XP_011520489 XM_011522188 XP_011520490 XM_011522189 XP_011520491 XM_011522190 XP_011520492 XM_011522191 XP_011520493 XM_011522192 XP_011520494 NM_001267580 NP_001254509 NM_003981 NP_003972 NM_199413 NP_955445 NM_199414
Function Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. {ECO:0000269|PubMed:12082078, ECO:0000269|PubMed:15297875, ECO:0000269|PubMed:15625105, ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:19468300, ECO:0000269|PubMed:20691902, ECO:0000269|PubMed:9885575}.
Subcellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Note=Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis.

PRC1 CRISPR/Cas9 KO Plasmid (h) - sc-401679 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 HDR Plasmid (h) - sc-401679-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 Double Nickase Plasmid (h) - sc-401679-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 Double Nickase Plasmid (h2) - sc-401679-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 CRISPR Activation Plasmid (h) - sc-401679-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 CRISPR Activation Plasmid (h2) - sc-401679-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 Lentiviral Activation Particles (h) - sc-401679-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 Lentiviral Activation Particles (h2) - sc-401679-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRC1 siRNA (h) - sc-44039 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRC1 shRNA Plasmid (h) - sc-44039-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRC1 shRNA (h) Lentiviral Particles - sc-44039-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRC1 RNAi - H00009055-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PRC1 RNAi - H00009055-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PRC1 RNAi - H00009055-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU100971 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN17364 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08372 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08372

PRC1 siRNA (Human) - CRH5976 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRC1 (NM_003981.3) - SHH382084 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRC1 siRNA - orb266478 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRC1 shRNA Plasmid (Human) - CHH5976 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRC1 miRNA 3'UTR clone - MiUTR3H-06012 from Creative biogene

Species Reactivities Human

PRC1 miRNA 3'UTR clone - MiUTR3H-06013 from Creative biogene

Species Reactivities Human
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