PIGR

Gene Symbol PIGR
Entrez Gene 5284
Alt Symbol -
Species Human
Gene Type protein-coding
Description polymeric immunoglobulin receptor
Other Description hepatocellular carcinoma associated protein TB6|hepatocellular carcinoma-associated protein TB6|poly-Ig receptor
Swissprots P01833 Q8IZY7 Q68D81
Accessions AAB23176 AAF72193 CAA03384 CAC10060 EAW93515 EAW93516 P01833 AF272149 AAN65630 AK225471 AK310199 AY178835 BC110061 BC110494 AAI10495 BC110495 AAI10496 CR749533 CAH18339 M24559 AAA36102 S62403 AAB20203 X73079 CAA51532 XM_011509629 XP_011507931 NM_002644 NP_002635
Function This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Top Pathways Intestinal immune network for IgA production

SC (C-2) - sc-374343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SC (C-2): sc-374343. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

SC (N-16) - sc-20485 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SC (N-16): sc-20485. Western blot analysis of SC expression in SK-MEL-28 (A), PC-3 (B), SK-BR-3 (C) and DU 145 (D) whole cell lysates.

SC (H-300) - sc-20656 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SC (H-300): sc-20656. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing membrane and cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

SC (SC-05) - sc-51694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

SC (C-20) - sc-20487 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SC (C-20): sc-20487. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

SC (0.N.556) - sc-59360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

SC (SPM217) - sc-56595 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-PIGR antibody - ab96196 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PIGR antibody (ab96196) at 1/1000 dilution + Molt4 whole cell lysate at 30 µg

Anti-PIGR antibody - ab91269 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PIGR antibody (ab91269) at 1/100 dilution + HL60 cell lysate at 35 µg

Anti-PIGR antibody - ab188814 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed paraffin embedded human kidney tissue labeling PIGR with ab188814 at 7.5 µg/ml

Anti-PIGR antibody - ab133391 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human small intestine tissue labelling PIGR with ab133391 antibody at 20µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-PIGR antibody - ab193122 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PIGR antibody (ab193122) at 2 µg/ml + HL60 cell lysateSecondaryGoat anti rabbit IgG at 1/10000 dilution

Anti-PIGR antibody - ab140937 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed, paraffin embedded Human small intestine tissue labelling PIGR with ab140937 at 2.5 µg/ml.

Anti-PIGR antibody [7C1] - ab170321 from Abcam

Prices $370.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 7C1

Anti-PIGR antibody [MM0865-23C17] - ab201658 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0865-23C17

Anti-PIGR Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A8430 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PIGR antibody LS-A8430 IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-PIGR Antibody (clone 7C1) - LS-C194896 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 7C1

Anti-PIGR Antibody (C-Terminus, AP) - LS-C245328 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody (C-Terminus, APC) - LS-C245329 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody (C-Terminus, Biotin) - LS-C245330 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody (C-Terminus, PE) - LS-C245333 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody (C-Terminus, FITC) - LS-C245331 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody (C-Terminus, Azide-free, HRP) - LS-C247759 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody - LS-C285579 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PIGR Antibody (aa135-237) - LS-C296001 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PIGR.
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