PIGR

Gene Symbol	PIGR
Entrez Gene	5284
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	polymeric immunoglobulin receptor
Other Description	hepatocellular carcinoma associated protein TB6|hepatocellular carcinoma-associated protein TB6|poly-Ig receptor
Swissprots	P01833 Q8IZY7 Q68D81
Accessions	AAB23176 AAF72193 CAA03384 CAC10060 EAW93515 EAW93516 P01833 AF272149 AAN65630 AK225471 AK310199 AY178835 BC110061 BC110494 AAI10495 BC110495 AAI10496 CR749533 CAH18339 M24559 AAA36102 S62403 AAB20203 X73079 CAA51532 XM_011509629 XP_011507931 NM_002644 NP_002635
Function	This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Top Pathways	Intestinal immune network for IgA production

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PIGR overexpression lysate - LY400939 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

Human PIGR (365 Ser/Gly) HEK293 Cell Lysate (WB positive control) - 10131-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PIGR Human Cells Transfected Lysate (positive control) (denatured) - orb172989 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

pIgR Overexpression Lysate (Native) - NBP2-04232 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Panoply™ Human PIGR Knockdown Stable Cell Line - CSC-DC011767 from Creative biogene Category Cell Line Species Human

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