COL8A1

Gene Symbol	COL8A1
Entrez Gene	1295
Alt Symbol	C3orf7
Species	Human
Gene Type	protein-coding
Description	collagen, type VIII, alpha 1
Other Description	cell proliferation-inducing protein 41|collagen VIII, alpha-1 polypeptide|collagen alpha-1(VIII) chain|endothelial collagen|smag-64|smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64
Swissprots	Q96D07 Q53XI6 P27658 D3DN42
Accessions	EAW79837 EAW79838 EAW79839 EAW79840 P27658 AF170702 AAF89665 AK311449 AL359062 AY550974 AAT52220 BC013581 AAH13581 BG938623 BQ774361 BT009917 AAP88919 CA393523 CB269463 CN484310 DA663372 DQ893873 ABM84799 X57527 CAA40748 NM_001850 NP_001841 NM_020351 NP_065084
Function	Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis. {ECO:0000269|PubMed:11708810}.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity	Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in cornea and sclera, and in the perichondrium of cartilaginous tissues. In the kidney, expressed in mesangial cells, glomerular endothelial cells, and tubular epithelial cells. Also expressed in mast cells, and in astrocytes during the repair process. Expressed in Descemet's membrane. Specifically expressed in peritoneal fibroblasts and mesothelial cells. {ECO:0000269|PubMed:10686422, ECO:0000269|PubMed:2376131, ECO:0000269|PubMed:7734329}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

COL8A1 overexpression lysate - LY412523 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COL8A1 overexpression lysate - LY419708 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

COL8A1 overexpression lysate - LY429081 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

COL8A1 293 Cell Lysate - 406138 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Collagen VIII alpha 1 Overexpression Lysate (Native) - NBL1-09357 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

COL8A1 Over-expression Lysate Product - GWB-E46B80 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Collagen VIII alpha 1 Overexpression Lysate (Native) - NBP2-11331 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Collagen VIII alpha 1 Overexpression Lysate (Native) - NBP2-10778 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human COL8A1 Knockdown Stable Cell Line - CSC-DC003470 from Creative biogene Category Cell Line Species Human

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