COL8A1

Gene Symbol COL8A1
Entrez Gene 1295
Alt Symbol C3orf7
Species Human
Gene Type protein-coding
Description collagen, type VIII, alpha 1
Other Description cell proliferation-inducing protein 41|collagen VIII, alpha-1 polypeptide|collagen alpha-1(VIII) chain|endothelial collagen|smag-64|smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64
Swissprots Q96D07 Q53XI6 P27658 D3DN42
Accessions EAW79837 EAW79838 EAW79839 EAW79840 P27658 AF170702 AAF89665 AK311449 AL359062 AY550974 AAT52220 BC013581 AAH13581 BG938623 BQ774361 BT009917 AAP88919 CA393523 CB269463 CN484310 DA663372 DQ893873 ABM84799 X57527 CAA40748 NM_001850 NP_001841 NM_020351 NP_065084
Function Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis. {ECO:0000269|PubMed:11708810}.
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in cornea and sclera, and in the perichondrium of cartilaginous tissues. In the kidney, expressed in mesangial cells, glomerular endothelial cells, and tubular epithelial cells. Also expressed in mast cells, and in astrocytes during the repair process. Expressed in Descemet's membrane. Specifically expressed in peritoneal fibroblasts and mesothelial cells. {ECO:0000269|PubMed:10686422, ECO:0000269|PubMed:2376131, ECO:0000269|PubMed:7734329}.

Human COL8A1 Gene cDNA Clone - orb142604 from Biorbyt

Prices $366.00
Sizes 10 μg
Species Human

Human-COL8A1-cDNA-Clone - DC03652 from Abgent, a WuXi AppTec company

Prices $1,004.40
Sizes 10 µg
Species Human
Accession BC013581

COL8A1 - MBS1274339 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC013581

Human COL8A1 ORF Clone(NM_001850.4) - CDCL159394 from Creative Biomart

Species Human
Accession NM_001850.4

Human COL8A1 ORF Clone (BC013581) - CDCS410474 from Creative biogene

Species Human
Accession P27658

Human COL8A1 ORF clone (BC013581) - CDCB160053 from Creative biogene

Species Human
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