COL8A1

Gene Symbol	COL8A1
Entrez Gene	1295
Alt Symbol	C3orf7
Species	Human
Gene Type	protein-coding
Description	collagen, type VIII, alpha 1
Other Description	cell proliferation-inducing protein 41|collagen VIII, alpha-1 polypeptide|collagen alpha-1(VIII) chain|endothelial collagen|smag-64|smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64
Swissprots	Q96D07 Q53XI6 P27658 D3DN42
Accessions	EAW79837 EAW79838 EAW79839 EAW79840 P27658 AF170702 AAF89665 AK311449 AL359062 AY550974 AAT52220 BC013581 AAH13581 BG938623 BQ774361 BT009917 AAP88919 CA393523 CB269463 CN484310 DA663372 DQ893873 ABM84799 X57527 CAA40748 NM_001850 NP_001841 NM_020351 NP_065084
Function	Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis. {ECO:0000269|PubMed:11708810}.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity	Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in cornea and sclera, and in the perichondrium of cartilaginous tissues. In the kidney, expressed in mesangial cells, glomerular endothelial cells, and tubular epithelial cells. Also expressed in mast cells, and in astrocytes during the repair process. Expressed in Descemet's membrane. Specifically expressed in peritoneal fibroblasts and mesothelial cells. {ECO:0000269|PubMed:10686422, ECO:0000269|PubMed:2376131, ECO:0000269|PubMed:7734329}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Collagen VIII alpha 1 peptide - ab138129 from Abcam Category Peptide Prices $176.00 Sizes 1 mg

COL8A1 / Collagen VIII Alpha 1 Antibody Blocking Peptide - LS-E4871 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

COL8A1-Antibody-N-term-Blocking-Peptide - BP17250a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human COL8a1 Protein - abx066014 from Abbexa Category Protein Source E.coli Species Human

Collagen Type VIII Alpha 1 (COL8a1), Human - 20-8386 from ARP American Research Products Category Protein Prices $869.00 Sizes 50 µg Source E.coli Species Human

COL8A1 fusion protein - ag10607 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human COL8A1, His-tagged - COL8A1-11440H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human COL8A1, His-tagged - COL8A1-140H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Collagen Type VIII Alpha 1 (COL8a1) - RPC146Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Collagen Type VIII Alpha 1 (COL8a1) - RPC146Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Collagen Type VIII Alpha 1 (COL8a1) - RPC146Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Collagen 8 alpha 1 Blocking Peptide - CBP1257 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Collagen Type VIII Alpha 1 (COL8a1) - RPC146Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Collagen alpha-1(VIII) chain(COL8A1) - CSB-YP005755HU CSB-EP005755HU CSB-BP005755HU CSB-MP005755HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Human COL8A1 protein (C-His) - orb311700 from Biorbyt Category Protein Prices $366.00, $629.00, $2,032.00, $2,882.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Collagen VIII alpha 1 Recombinant Protein Antigen - NBP2-13856PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

COL8A1 Peptide, Human - M34GP03470H from Creative Peptides Category Peptide Source Synthetic. Species Human

COL8A1 Recombinant Protein (OPCD02344) - OPCD02344 from Aviva Systems Biology Category Protein Source E.coli Species Human

Collagen alpha-1(VIII) Chain Recombinant Protein - 91-692 from ProSci Category Protein Prices $525.00 Sizes 50 µg Source Human Cells Species Human

Human Collagen VIII protein - orb391503 from Biorbyt Category Protein Prices $374.00, $901.00, $3,536.00 Sizes 10 μl (Trial size), 50 μl, 500 μl Species Human

COL8A1, Recombinant Protein - MBS8248813 from MyBioSource Category Protein Prices $255.00, $635.00, $2,370.00 Sizes 10 µg, 50 µg, 500 µg Source Human cells Species Human

Collagen alpha-1 (VIII) chain (COL8A1), Recombinant Protein - MBS958828 from MyBioSource Category Protein Prices $1,525.00, $1,525.00, $1,755.00, $1,755.00, $2,615.00, $2,615.00, $3,060.00, $3,060.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Collagen Type VIII Alpha 1 (COL8a1), Recombinant Protein - MBS2011224 from MyBioSource Category Protein Prices $290.00, $690.00, $1,080.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Recombinant Human Collagen α-1(VIII) Chain,COL8A1 (C-6His) - AP75414 from Signalway Antibody Category Protein Prices $349.00, $749.00, $2,289.00, $3,209.00 Sizes 10 µg, 50 µg, 500 µg, 1 mg Source Human Cells Species Human

Collagen VIII peptide - orb217120 from Biorbyt Category Peptide Species Human, Mouse, Rat

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