Gene Symbol | PCSK2 |
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Entrez Gene | 5126 |
Alt Symbol | NEC 2, NEC-2, NEC2, PC2, SPC2 |
Species | Human |
Gene Type | protein-coding |
Description | proprotein convertase subtilisin/kexin type 2 |
Other Description | KEX2-like endoprotease 2|neuroendocrine convertase 2|prohormone convertase 2 |
Swissprots | Q8IWA8 Q14927 Q9UJC6 Q5JYQ1 B4DFQ3 P16519 B1ANH9 Q9NQG3 Q9NUG1 |
Accessions | AAA59919 AAB32656 AAC51862 AAD14202 EAX10279 EAX10280 EAX10281 P16519 AK091505 AK294200 BAG57514 AK312341 BAG35262 BC001905 BC005815 AAH05815 BC040546 AAH40546 BM893758 BP384064 CD519990 DA147868 DA148468 DB173053 DQ892675 ABM83601 DQ895917 ABM86843 HY137524 J05252 AAA60032 NM_001201528 NP_001188457 NM_001201529 NP_001188458 NM_002594 NP_002585 |
Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells. {ECO:0000269|PubMed:9287128}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules. |
Human Proprotein Convertase 2 protein fragment - ab132982 from Abcam
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Human Proprotein Convertase 2 protein fragment - ab159067 from Abcam
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Proprotein Convertase 2 peptide - ab5012 from Abcam
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Proprotein Convertase 2 peptide - ab41404 from Abcam
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Proprotein Convertase 2 peptide - ab41408 from Abcam
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PCSK2 Antibody Blocking Peptide - LS-E21791 from LifeSpan Bioscience
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PCSK2 Antibody Blocking Peptide - LS-E9109 from LifeSpan Bioscience
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PCSK2 Antibody Blocking Peptide - LS-E9110 from LifeSpan Bioscience
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Recombinant Human Proprotein Convertase 2/PCSK2 Protein - H00005126-Q01 from Novus Biologicals
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Recombinant Human Proprotein Convertase 2/PCSK2 Protein - H00005126-P01 from Novus Biologicals
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PCSK2-Antibody-Center-Blocking-Peptide - BP7617c from Abgent, a WuXi AppTec company
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PCSK2-Antibody-N-term-Blocking-Peptide - BP7617a from Abgent, a WuXi AppTec company
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Recombinant Human Proprotein Convertase 2/PCSK2, CF - 6018-SE-010 from R&D Systems
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PCSK2 Blocking Peptide - 33R-4799 from Fitzgerald
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NEC2 - H00005126-P01-10 from Acris Antibodies
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NEC2 - H00005126-P01-25 from Acris Antibodies
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NEC2 - H00005126-Q01-10 from Acris Antibodies
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NEC2 - H00005126-Q01-25 from Acris Antibodies
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NEC2 control peptide - SP5137CP from Acris Antibodies
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PCSK2 fusion protein - ag0852 from Proteintech Group
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Recombinant Human PCSK2, His-tagged - PCSK2-88H from Creative Biomart
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Recombinant Proprotein Convertase Subtilisin/Kexin Type 2 (PCSK2) - RPE182Hu01 from Uscn Life Science Inc.
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Recombinant Human Neuroendocrine convertase 2(PCSK2) - CSB-YP017642HU CSB-EP017642HU CSB-BP017642HU CSB-MP017642HU from Cusabio
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Recombinant Human Proprotein Convertase 2/PCSK2 Protein, CF - 6018-SE from R&D Systems
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NEC2 - TP322498 from Acris Antibodies
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