Gene Symbol | CBX2 |
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Entrez Gene | 84733 |
Alt Symbol | CDCA6, M33, SRXY5 |
Species | Human |
Gene Type | protein-coding |
Description | chromobox homolog 2 |
Other Description | Pc class homolog|cell division cycle associated 6|chromobox homolog 2 (Pc class homolog, Drosophila)|chromobox protein homolog 2|modifier 3 |
Swissprots | Q9BTB1 Q14781 Q0VDA5 |
Accessions | CAA54839 EAW89568 EAW89569 Q14781 AL157459 BC004252 AAH04252 BC119759 AAI19760 BC119760 AAI19761 BC156118 AAI56119 BC157074 AAI57075 BX110913 CN367085 CN367087 CN367098 CV815254 DB452048 EU446542 ABZ92071 XM_011525382 XP_011523684 XM_011525383 XP_011523685 NM_005189 NP_005180 NM_032647 NP_116036 |
Function | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression. {ECO:0000269|PubMed:19361780, ECO:0000269|PubMed:21282530}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21282530}. |
Human CBX2 peptide - ab91615 from Abcam
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Human CBX2 protein fragment - ab153555 from Abcam
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Human CBX2 protein fragment - ab153556 from Abcam
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Human CBX2 protein fragment - ab198750 from Abcam
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Human CBX2 protein fragment - ab198759 from Abcam
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CBX2 Antibody Blocking Peptide - LS-E4772 from LifeSpan Bioscience
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CBX2 Antibody Blocking Peptide - LS-E21348 from LifeSpan Bioscience
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CBX2 Antibody Blocking Peptide - LS-E10215 from LifeSpan Bioscience
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TUSC3 Antibody Blocking Peptide - LS-E26639 from LifeSpan Bioscience
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Recombinant Human Cbx2 Protein - H00084733-Q02 from Novus Biologicals
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Recombinant Human Cbx2 Protein - H00084733-Q01 from Novus Biologicals
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CBX2-Antibody-Center-Blocking-Peptide - BP17146c from Abgent, a WuXi AppTec company
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CBX2-Antibody-N-term-Blocking-Peptide - BP9605a from Abgent, a WuXi AppTec company
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CBX2 blocking peptide - GTX89252-PEP from GeneTex
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CBX2 Peptide - AC21-1005-P from Abcore
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CBX2 - H00084733-Q01-10 from Acris Antibodies
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CBX2 - H00084733-Q01-25 from Acris Antibodies
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CBX2 - H00084733-Q02 from Acris Antibodies
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CBX2 - H00084733-Q02-10 from Acris Antibodies
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CBX2 - H00084733-Q02-25 from Acris Antibodies
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CBX2 fusion protein - Ag8311 from Proteintech Group
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CBX2 fusion protein - ag7979 from Proteintech Group
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Recombinant Human CBX2, His-tagged - CBX2-10767H from Creative Biomart
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Recombinant Human Chromobox protein homolog 2(CBX2) - CSB-YP613521HU CSB-EP613521HU CSB-BP613521HU CSB-MP613521HU from Cusabio
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CBX2 (N-term HIS tag, transcript variant 2) - TP760360 from Acris Antibodies
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