CBX2

Gene Symbol CBX2
Entrez Gene 84733
Alt Symbol CDCA6, M33, SRXY5
Species Human
Gene Type protein-coding
Description chromobox homolog 2
Other Description Pc class homolog|cell division cycle associated 6|chromobox homolog 2 (Pc class homolog, Drosophila)|chromobox protein homolog 2|modifier 3
Swissprots Q9BTB1 Q14781 Q0VDA5
Accessions CAA54839 EAW89568 EAW89569 Q14781 AL157459 BC004252 AAH04252 BC119759 AAI19760 BC119760 AAI19761 BC156118 AAI56119 BC157074 AAI57075 BX110913 CN367085 CN367087 CN367098 CV815254 DB452048 EU446542 ABZ92071 XM_011525382 XP_011523684 XM_011525383 XP_011523685 NM_005189 NP_005180 NM_032647 NP_116036
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression. {ECO:0000269|PubMed:19361780, ECO:0000269|PubMed:21282530}.
Subcellular Location Nucleus {ECO:0000269|PubMed:21282530}.

M33 (N-20) - sc-19295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
M33 (N-20): sc-19295. Western blot analysis of M33 expression in HEK293 (A), HeLa (B), MDA-MB-231 (C) and P19 (D) whole cell lysates and HeLa nuclear extract (E).

M33 (34) - sc-136387 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
M33 (34): sc-136387. Western blot analysis of M33 expression in P19 whole cell lysate.

M33 (C-18) - sc-19297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

M33 (H-97) - sc-366649 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
M33 (H-97): sc-366649. Western blot analysis of M33 expression in MES-SA/D x5 whole cell lysate (A) and NIH/3T3 nuclear extract (B).

M33 (Y-23) - sc-133768 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
M33 (Y-23): sc-133768. Western blot analysis of M33 expression in human heart tissue extract.

Anti-CBX2 antibody - ab80044 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CBX2 antibody (ab80044) at 1 µg/mlLane 1 : JEG-3 (Human placental choriocarcinoma cell line) Whole Cell Lysate Lane 2 : HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell LysateLane 3 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 4 : MEL-1 (Human embryonic stem cell, male cell line) Whole Cell Lysate (ab27198)Lane 5 : MEL-2 (Human embryonic stem cell, female cell line) Whole Cell Lysate (ab27196)Lane 6 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CBX2 antibody - ab127191 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CBX2 antibody (ab127191) at 1/1000 dilution + A431 cell lysate at 30 µg

Anti-CBX2 antibody - ab182620 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CBX2 antibody (ab182620) at 1/350 dilutionLane 1 : Human ovarian cancer tissue lysateLane 2 : Mouse heart tissue lysateLysates/proteins at 30 µg per lane.SecondaryGoat anti Rabbit IgG - H&L HRP conjugated antibody at 1/10000 dilutiondeveloped using the ECL technique

Anti-cbx2 antibody - ab57890 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57890 cbx2 antibody at 1ug/ml.

Anti-CBX2 antibody [EPR12624] - C-terminal - ab184968 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12624
All lanes : Anti-CBX2 antibody [EPR12624] - C-terminal (ab184968) at 1/50000 dilutionLane 1 : HeLa cell lysateLane 2 : 293 cell lysateLane 3 : NIH:OVCAR-3 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-CBX2 Antibody (aa137-166, Azide-free, HRP) - LS-C249580 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (aa137-166, APC) - LS-C233413 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (aa137-166, AP) - LS-C233412 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (C-Terminus) - LS-C116791 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CBX2 antibody LS-C116791 Western blot of OVCAR-3 cell lysate.

Anti-CBX2 Antibody (aa137-166, Biotin) - LS-C233414 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (aa137-166, FITC) - LS-C233415 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (aa107-156) - LS-C81651 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-CBX2 Antibody (aa47-75) - LS-C168363 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of CBX2 Antibody in MDA-MB231 cell line lysates (35 ug/lane). CBX2 (arrow) was detected using the purified antibody.

Anti-CBX2 Antibody (aa137-166) - LS-C159274 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CBX2 Antibody western blot of mouse testis tissue lysates (35 ug/lane). The CBX2 antibody detected the CBX2 protein (arrow).

Anti-CBX2 Antibody (N-Terminus, AP) - LS-C233417 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (aa137-166, PE) - LS-C233416 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (N-Terminus, APC) - LS-C233419 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (N-Terminus, PE) - LS-C233421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (N-Terminus, Biotin) - LS-C233418 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBX2 Antibody (N-Terminus, FITC) - LS-C233420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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