IL15RA

Gene Symbol	IL15RA
Entrez Gene	3601
Alt Symbol	CD215
Species	Human
Gene Type	protein-coding
Description	interleukin 15 receptor, alpha
Other Description	interleukin 15 receptor alpha isoform EM2|interleukin 15 receptor alpha isoform IC2|interleukin 15 receptor alpha isoform IC3|interleukin 15 receptor alpha isoform IC4|interleukin 15 receptor alpha isoform IC5|interleukin 15 receptor alpha isoform IC6|interleukin 15 receptor alpha isoform IC7|interleukin 15 receptor alpha isoform IC8|interleukin-15 receptor subunit alpha
Swissprots	Q6B0J2 Q13261 Q7LDR4 Q3B769 Q5JVA2 Q5JVA4 B4E2C2 Q7Z609 Q5JVA1
Accessions	AAP69528 CCA64145 CCA64146 EAW86415 EAW86416 EAW86417 EAW86418 EAW86419 EAW86420 EAW86421 EAW86422 Q13261 AA847313 AF035279 AAB88175 AK304211 BAG65084 BC065506 AAH65506 BC074726 AAH74726 BC107777 AAI07778 BC121140 AAI21141 BC121141 AAI21142 BM546106 CR457064 CAG33345 CR542023 CAG46820 DC298692 HQ401283 AEP26933 JX987304 AFY11387 JX987305 AFY11388 JX987306 AFY11389 JX987307 AFY11390 JX987308 AFY11391 JX987309 AFY11392 JX987310 AFY11393 JX987311 AFY11394 U31628 AAC50312 XM_011519461 XP_011517763 XM_011519462 XP_011517764 XM_011519463 XP_011517765 XM_011519464 XP_011517766 XM_011519465 XP_011517767 XM_011519466 XP_011517768 XM_011519467 XP_011517769 XM_011519468 XP_011517770 XM_011519469 XP_011517771 XM_011519470 XP_011517772 XM_011519471 XP_011517773 XM_011519472 XP_011517774 XM_011519473 XP_011517775 XM_011519474 XP_011517776 XM_011519475 XP_011517777 XM_011519476 XP_011517778 XM_011519477 XP_011517779 NM_001243539 NP_001230468 NM_001256765 NP_001243694 NM_002189 NP_002180 NM_172200 NP_751950 NR_046362
Function	High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK. {ECO:0000269|PubMed:11714793, ECO:0000269|PubMed:8530383}.
Subcellular Location	Isoform 8: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, Golgi and cytoplasmic vesicles, but not with the nuclear membrane.
Tissue Specificity	Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures. {ECO:0000269|PubMed:10480910, ECO:0000269|PubMed:12114302, ECO:0000269|PubMed:8530383}.
Top Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Intestinal immune network for IgA production, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse IL15RA ELISA Kit (Sandwich ELISA) - LS-F2851 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 125-8000 pg/ml

Mouse IL-15 R alpha DuoSet ELISA - DY551 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Interleukin-15 receptor subunit alpha (IL15RA), Human, ELISA Kit - CSB-EL011594HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Interleukin-15 receptor subunit alpha, IL15RA, Human, ELISA Kit - E1035h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 62.5-4000 pg/mL

interleukin 15 receptor, alpha, ELISA Kit - MBS942463 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human IL15RA is typically less than 7.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 31.25 pg/ml-2000 pg/ml.

Interleukin 2 Receptor Alpha, ELISA Kit - MBS090121 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS075542 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS064800 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS086874 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS101986 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS097640 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS080498 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 10 pg/ml Range 62.5 pg/ml - 2000 pg/ml

Interleukin 2 Receptor Alpha, ELISA Kit - MBS100727 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS096646 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS055431 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS083597 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS090518 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS062102 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS075418 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS080794 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS067029 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS061655 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS055258 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS088543 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Interleukin 2 Receptor Alpha, ELISA Kit - MBS067558 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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