RASSF2

Gene Symbol RASSF2
Entrez Gene 9770
Alt Symbol CENP-34, RASFADIN
Species Human
Gene Type protein-coding
Description Ras association (RalGDS/AF-6) domain family member 2
Other Description Ras association (RalGDS/AF-6) domain family 2|centromere protein 34|ras association domain-containing protein 2
Swissprots Q53HD0 A8K5Z3 A6NIX9 P50749 Q8IZA5 Q17S06 Q6AHZ2
Accessions EAX10445 P50749 AK222650 BAD96370 AK291458 BAF84147 AK307232 AY154470 AAN59975 AY154471 AAN59976 AY154472 AAN59977 BC110385 AAI10386 BC117118 AAI17119 BC117120 AAI17121 CR627436 CAH10522 D79990 BAA11485 DA333367 HQ258175 ADR82929 XM_005260895 XP_005260952 XM_011529410 XP_011527712 XM_011529411 XP_011527713 XM_011529412 XP_011527714 NM_014737 NP_055552 NM_170774 NP_739580
Function Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. {ECO:0000269|PubMed:12732644, ECO:0000269|PubMed:16012945, ECO:0000269|PubMed:19525978}.
Subcellular Location Nucleus. Cytoplasm. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.
Tissue Specificity Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines. {ECO:0000269|PubMed:12732644}.

RASSF2 (E-11) - sc-376347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RASSF2 (E-11): sc-376347. Western blot analysis of RASSF2 expression in CCRF-CEM nuclear extract.

RASSF2 (H-53) - sc-67148 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

RASSF2 (P-17) - sc-46475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RASSF2 (P-17): sc-46475. Western blot analysis of RASSF2 expression in CCRF-CEM whole cell lysate.

RASSF2 (N-14) - sc-46474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RASSF2 (M-53) - sc-67149 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

RASSF2 (Y-17) - sc-46476 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-RASSF2 antibody - ab97617 from Abcam

Prices $304.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-RASSF2 antibody (ab97617) at 1/500 dilution + Raji whole cell lysate at 30 µg

Anti-RASSF2 antibody - ab203580 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded rat brain tissue sections labeling RASSF2 with ab203580 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-RASSF2 antibody - ab138124 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RASSF2 antibody (ab138124) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-RASSF2 antibody - ab130982 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RASSF2 antibody (ab130982) at 1 µg/ml + Human placenta lysate at 10 µgSecondaryGoat anti-Rabbit IgG HRP

Anti-RASSF2 antibody [EPR6621] - ab124786 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6621
All lanes : Anti-RASSF2 antibody [EPR6621] (ab124786) at 1/1000 dilutionLane 1 : Raji cell lysateLane 2 : Jurkat cell lysateLane 3 : SH-SY5Y cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-RASSF2 Antibody (aa11-22) IHC-plus™ - LS-B3828 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-RASSF2 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3828 concentration 3.75 ug/ml.

Anti-RASSF2 Antibody (aa152-197) - LS-C313910 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RASSF2 Antibody (aa93-142) - LS-C200571 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using RASSF2 antibody.

Anti-RASSF2 Antibody (C-Terminus) - LS-C151662 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RASSF2 antibody Western Blot of Placenta.

Anti-RASSF2 Antibody (C-Terminus, clone EPR6621) - LS-C138945 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6621
Western blot analysis on (A) Raji, (B) Jurkat, and (C) SH-SY5Y cell lysates using anti-RASSF2 antibody.

Anti-RASSF2 Antibody (aa109-158) - LS-C120298 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using RASSF2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-RASSF2 Antibody (aa1-293) - LS-C185875 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence of paraformaldehyde-fixed A549 using RASSF2 antibody at 1:200 dilution.

RASSF2 Antibody [Unconjugated] - AF5639 from Novus Biologicals

Prices $99.00, $329.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of Jurkat human acute T cell leukemia cell line, Raji human Burkitt's lymphoma cell line, CEM human T‑lymphoblastoid cell line, and Daudi human Burkitt's lymphoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse RASSF2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5639) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for RASSF2 at approximately 40 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

RASSF2 Antibody - NBP1-32571 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RASSF2 Antibody - NBP2-13206 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RASSF2 Antibody [NBP2-13206] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4

RASSF2 Antibody - NBP1-52475 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: RASSF2 Antibody [NBP1-52475] - Analysis of anti-RASSF2 antibody with human spleen at concentration 3.75 ug/ml.

RASSF2 Polyclonal Antibody - bs-2939R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-RASSF2 Polyclonal Antibody, Unconjugated (bs-2939R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Anti-RASSF2 antibody produced in rabbit - SAB2700351 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-RASSF2: <B>Cat. No. SAB2700351</B>: Immunofluorescence analysis of paraformaldehyde-fixed A549, using RASSF2 antibody at 1:200 dilution.

Anti-RASSF2 antibody produced in rabbit - HPA051200 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RASSF2:<B>Cat. No. HPA051200</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells of tubules.
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