SF3B1

Gene Symbol SF3B1
Entrez Gene 23451
Alt Symbol Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155
Species Human
Gene Type protein-coding
Description splicing factor 3b, subunit 1, 155kDa
Other Description SAP 155|pre-mRNA processing 10|pre-mRNA splicing factor SF3b, 155 kDa subunit|spliceosome-associated protein 155|splicing factor 3B subunit 1|splicing factor 3b, subunit 1, 155kD
Swissprots E9PCH3 O75533
Accessions EAW70146 O75533 AF054284 AAC97189 AF070540 AAC28633 AF086296 AK057684 AK290470 BAF83159 AK294851 BAG57955 AK308122 AL137410 CAB70728 BC015530 AAH15530 BC029418 AAH29418 BC039020 BC046140 BC056155 AAH56155 BC064335 BC107883 AAI07884 BE168209 BE168220 CD692669 HY054349 XM_011510867 XP_011509169 XM_011510868 XP_011509170 XR_241300 XR_241302 NM_001005526 NP_001005526 NM_001308824 NP_001295753 NM_012433 NP_036565
Function Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location Nucleus speckle. Note=During mitosis, transiently dispersed from the nuclear speckles to the cytoplasm.
Top Pathways Spliceosome

Splicing factor 3B subunit 1 (SF3B1), Human, ELISA Kit - CSB-EL021125HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

splicing factor 3b, subunit 1, 155kDa, ELISA Kit - MBS902512 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 11.7 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Human Splicing factor 3B subunit 1(SF3B1) ELISA kit - CSB-EL021125HU from Cusabio

Category ELISA Kit
Sensitivity 11.7pg/ml
Range 46.88 pg/ml-3000 pg/ml

Human Splicing factor 3B subunit 1 (SF3B1) ELISA Kit - EKC35656 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 11.7 pg/ml
Range 46.88 pg/ml-3000 pg/ml

Human SF3B1 ELISA Kit - E036495 from Biobool

Category ELISA Kit
Sensitivity 11.7 pg/ml

SF3B1 ELISA Kit (Human) (OKCA01530) - OKCA01530 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 11.7 pg/mL
Range 46.88 - 3,000 pg/mL
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