SPRED1

Gene Symbol	SPRED1
Entrez Gene	161742
Alt Symbol	NFLS, PPP1R147, hSpred1, spred-1
Species	Human
Gene Type	protein-coding
Description	sprouty-related, EVH1 domain containing 1
Other Description	protein phosphatase 1, regulatory subunit 147|sprouty-related, EVH1 domain-containing protein 1|suppressor of Ras/MAPK activation
Swissprots	Q8N256 Q05D53 B2RPJ8 Q7Z699
Accessions	CCQ43858 EAW92368 Q7Z699 AK091222 BAC03614 AK095219 AY299089 AAP59414 BC018015 AAH18015 BC137480 AAI37481 BC137481 AAI37482 BX538234 DA405650 XM_005254202 XP_005254259 XM_005254203 XP_005254260 XM_011521288 XP_011519590 XM_011521289 XP_011519591 XM_011521290 XP_011519592 NM_152594 NP_689807
Function	Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16115197}; Peripheral membrane protein {ECO:0000269|PubMed:16115197}. Membrane, caveola {ECO:0000269|PubMed:16115197}; Peripheral membrane protein {ECO:0000269|PubMed:16115197}. Nucleus {ECO:0000269|PubMed:16115197}. Note=Localized in cholesterol-rich membrane raft/caveola fractions.
Tissue Specificity	Weakly expressed in embryonic cell line HEK293. {ECO:0000269|PubMed:15580519}.
Top Pathways	Jak-STAT signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPRED1 full length protein - ab187437 from Abcam Category Protein Source E. coli Species Human

SPRED1 Antibody Blocking Peptide - LS-E3328 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPRED1 Antibody Blocking Peptide - LS-E3330 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPRED1 Antibody Blocking Peptide - LS-E30584 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SPRED1 Antibody Blocking Peptide - LS-E30589 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SPRED1 Peptide - P0421 from Novus Biologicals Category Peptide Species Human

SPRED1 Peptide - P0423 from Novus Biologicals Category Peptide Species Human

SPRED1-Antibody-N-term-Blocking-Peptide - BP1449d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPRED1-Antibody-C-term-Blocking-Peptide - BP1449b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Spred1 Peptide - GTX85376-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Spred1 Peptide - GTX85377-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

SPRED1 protein (His tag) - 80R-3988 from Fitzgerald Category Protein Prices $375.00 Sizes 50 µg Source E.coli

SPRED1 (1-444, His-tag) - AR51673PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

SPRED1 (1-444, His-tag) - AR51673PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

SPRED1 Control Peptide - AP30821CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SPRED1 Control Peptide - AP30822CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Spred1 Peptide - 4833P from ProSci Category Peptide Species Human

Spred1 Peptide - 4843P from ProSci Category Peptide Species Human

SPRED1 fusion protein - ag19209 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SPRED1 fusion protein - ag19705 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human sprouty-related, EVH1 domain containing 1, His-tagged - SPRED1-630H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Sprouty-related, EVH1 domain-containing protein 1(SPRED1) - CSB-YP773600HU CSB-EP773600HU CSB-BP773600HU CSB-MP773600HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPRED1, 1-444aa, Human, His tag, E.coli (Denatured) - ATGP2853 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

SPRED1 Recombinant Protein Antigen - NBP1-89836PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SPRED1 Peptide, Human - M34GP15089H from Creative Peptides Category Peptide Source Synthetic. Species Human

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