SPRED1

Gene Symbol SPRED1
Entrez Gene 161742
Alt Symbol NFLS, PPP1R147, hSpred1, spred-1
Species Human
Gene Type protein-coding
Description sprouty-related, EVH1 domain containing 1
Other Description protein phosphatase 1, regulatory subunit 147|sprouty-related, EVH1 domain-containing protein 1|suppressor of Ras/MAPK activation
Swissprots Q8N256 Q05D53 B2RPJ8 Q7Z699
Accessions CCQ43858 EAW92368 Q7Z699 AK091222 BAC03614 AK095219 AY299089 AAP59414 BC018015 AAH18015 BC137480 AAI37481 BC137481 AAI37482 BX538234 DA405650 XM_005254202 XP_005254259 XM_005254203 XP_005254260 XM_011521288 XP_011519590 XM_011521289 XP_011519591 XM_011521290 XP_011519592 NM_152594 NP_689807
Function Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16115197}; Peripheral membrane protein {ECO:0000269|PubMed:16115197}. Membrane, caveola {ECO:0000269|PubMed:16115197}; Peripheral membrane protein {ECO:0000269|PubMed:16115197}. Nucleus {ECO:0000269|PubMed:16115197}. Note=Localized in cholesterol-rich membrane raft/caveola fractions.
Tissue Specificity Weakly expressed in embryonic cell line HEK293. {ECO:0000269|PubMed:15580519}.
Top Pathways Jak-STAT signaling pathway

SPRED1 CRISPR/Cas9 KO Plasmid (h) - sc-402981 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 HDR Plasmid (h) - sc-402981-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 Double Nickase Plasmid (h) - sc-402981-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 Double Nickase Plasmid (h2) - sc-402981-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 CRISPR Activation Plasmid (h) - sc-402981-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 CRISPR Activation Plasmid (h2) - sc-402981-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 Lentiviral Activation Particles (h) - sc-402981-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 Lentiviral Activation Particles (h2) - sc-402981-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPRED1 siRNA (h) - sc-90024 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPRED1 shRNA Plasmid (h) - sc-90024-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPRED1 shRNA (h) Lentiviral Particles - sc-90024-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU033321 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20513 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20513 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11445 from Sigma-Aldrich

Category miRNA

SPRED1 siRNA (Human) - CRJ5932 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPRED1 - MBS8225725 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SPRED1 (NM_152594.2) - SHH417176 from Creative biogene

Category siRNA
Species Reactivities Human

Human SPRED1 siRNA - orb276433 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPRED1 shRNA Plasmid (Human) - CHJ5932 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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