PLTP

Gene Symbol	PLTP
Entrez Gene	5360
Alt Symbol	BPIFE, HDLCQ9
Species	Human
Gene Type	protein-coding
Description	phospholipid transfer protein
Other Description	BPI fold containing family E|lipid transfer protein II
Swissprots	B4DDD5 Q9BR07 Q8WTT1 B4DRB4 E1P5N8 A8K006 Q9BSH8 E7EV16 P55058
Accessions	AAR87775 EAW75781 EAW75782 EAW75783 EAW75784 EAW75785 EAW75786 EAW75787 P55058 AB076694 BAB79630 AF052157 AK092397 AK092523 AK097009 BAG53407 AK222690 BAD96410 AK289371 BAF82060 AK293150 BAG56696 AK299181 BAG61226 BC005045 AAH05045 BC019847 AAH19847 BC019898 AAH19898 DQ891798 ABM82724 DQ894981 ABM85907 L26232 AAA36443 NM_001242920 NP_001229849 NM_001242921 NP_001229850 NM_006227 NP_006218 NM_182676 NP_872617
Function	Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.
Subcellular Location	Secreted.
Tissue Specificity	Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.
Top Pathways	PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PLTP 293T Cell Transient Overexpression Lysate(Denatured) - H00005360-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PLTP overexpression lysate - LY401875 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PLTP overexpression lysate - LY405442 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PLTP 293 Cell Lysate - 401670 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PLTP Overexpression Lysate (Denatured) - H00005360-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

PLTP Overexpression Lysate (Native) - NBL1-14528 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PLTP Over-expression Lysate Product - GWB-8B1713 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human PLTP HEK293 Cell Lysate (WB positive control) - 11171-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

PLTP Overexpression Lysate (Native) - NBP2-04830 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Human PLTP Human Cells Transfected Lysate (positive control) (denatured) - orb179360 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human PLTP Knockdown Stable Cell Line - CSC-DC011983 from Creative biogene Category Cell Line Species Human

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