PLTP

Gene Symbol PLTP
Entrez Gene 5360
Alt Symbol BPIFE, HDLCQ9
Species Human
Gene Type protein-coding
Description phospholipid transfer protein
Other Description BPI fold containing family E|lipid transfer protein II
Swissprots B4DDD5 Q9BR07 Q8WTT1 B4DRB4 E1P5N8 A8K006 Q9BSH8 E7EV16 P55058
Accessions AAR87775 EAW75781 EAW75782 EAW75783 EAW75784 EAW75785 EAW75786 EAW75787 P55058 AB076694 BAB79630 AF052157 AK092397 AK092523 AK097009 BAG53407 AK222690 BAD96410 AK289371 BAF82060 AK293150 BAG56696 AK299181 BAG61226 BC005045 AAH05045 BC019847 AAH19847 BC019898 AAH19898 DQ891798 ABM82724 DQ894981 ABM85907 L26232 AAA36443 NM_001242920 NP_001229849 NM_001242921 NP_001229850 NM_006227 NP_006218 NM_182676 NP_872617
Function Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.
Subcellular Location Secreted.
Tissue Specificity Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.
Top Pathways PPAR signaling pathway

Human PLTP full length protein - ab114581 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114581 at approximately 72.05kDa stained with Coomassie Blue.

PLTP Antibody Blocking Peptide - LS-E22421 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

PLTP Antibody Blocking Peptide - LS-E9112 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human PLTP Protein - H00005360-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

PLTP-Antibody-C-term-Blocking-Peptide - BP7620b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human HDLCQ9 protein - orb84137 from Biorbyt

Category Protein
Prices $323.00, $612.00
Sizes 20 μg, 50 μg
Source Human
Species Human
SDS-PAGE analysis of Human PLTP His tag protein

Human PLTP protein - orb244449 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human PLTP protein - orb245960 from Biorbyt

Category Protein
Prices $213.00, $408.00, $680.00, $1,122.00, $1,777.00
Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg
Species Human

PLTP Blocking Peptide - 33R-6693 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

PLTP Blocking Peptide - 33R-10824 from Fitzgerald

Category Peptide
Prices $115.00
Sizes 50 µg

PLTP - H00005360-P01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

PLTP control peptide - AP00266CP-N from Acris Antibodies

Category Peptide
Prices $205.00
Sizes 50 µg

PLTP fusion protein - Ag8171 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PLTP fusion protein - ag0681 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

PLTP fusion protein - Ag5644 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

PLTP fusion protein - Ag8096 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human PLTP, His tagged - PLTP-3781H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human PLTP - PLTP-30291TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human PLTP, His-tagged - PLTP-1800H from Creative Biomart

Category Protein
Source E.coli
Species Human

Human GITR Ligand Recombinant, Fc - RKQ9UNG2 from Reprokine

Category Protein
Prices $160.00, $550.00, $1,950.00
Sizes 10 µg, 50 µg, 200 µg
Source Optimized DNA sequence encoding Human GITR Ligand -GITRL (GLN50 - SER177 ) mature chain including a C-terminal His tag was expressed in HEK293 cells.
Species Human

Human Phospholipid Transfer Protein Recombinant - RKP55058 from Reprokine

Category Protein
Prices $160.00, $550.00, $1,950.00
Sizes 20 µg, 100 µg, 500 µg
Source Optimized DNA sequence encoding Human Phospholipid Transfer Protein -PLTP (VAL18 - VAL493) mature chain including a C-terminal His tag was expressed in HEK293 cells.
Species Human

Recombinant Phospholipid Transfer Protein (PLTP) - RPC728Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Phospholipid Transfer Protein (PLTP) - RPC728Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Phospholipid Transfer Protein (PLTP) - RPC728Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Phospholipid Transfer Protein (PLTP) - RPC728Ra01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Rat
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