NAGPA

Gene Symbol NAGPA
Entrez Gene 51172
Alt Symbol APAA, UCE
Species Human
Gene Type protein-coding
Description N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Other Description alpha-N-acetylglucosaminyl phosphodiesterase|lysosomal alpha-N-acetylglucosaminidase|mannose 6-phosphate-uncovering enzyme|phosphodiester alpha-GlcNAcase
Swissprots B2RAS1 Q96EJ8 Q9UK23
Accessions EAW85245 EAW85246 Q9UK23 AF052111 AF187072 AAF08273 AK025570 AK026122 AK092889 AK127952 BAG54605 AK302916 BAG64081 AK314320 BAG36968 BC012194 AAH12194 DA879815 XM_011522517 XP_011520819 XM_011522518 XP_011520820 XM_011522519 XP_011520821 XR_243285 NM_016256 NP_057340
Function Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P- mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N- acetylglucosaminyltransferases. {ECO:0000269|PubMed:23572527}.
Subcellular Location Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:12058031}; Single-pass type I membrane protein {ECO:0000269|PubMed:12058031}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:12058031}. Note=Cis/medial Golgi.
Tissue Specificity Isoform 2 may be brain-specific.
Top Pathways Lysosome

NAGPA CRISPR/Cas9 KO Plasmid (h) - sc-412139 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA HDR Plasmid (h) - sc-412139-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA Double Nickase Plasmid (h) - sc-412139-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA Double Nickase Plasmid (h2) - sc-412139-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA CRISPR Activation Plasmid (h) - sc-412139-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA CRISPR Activation Plasmid (h2) - sc-412139-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA Lentiviral Activation Particles (h) - sc-412139-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA Lentiviral Activation Particles (h2) - sc-412139-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NAGPA siRNA (h) - sc-93182 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAGPA shRNA Plasmid (h) - sc-93182-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAGPA shRNA (h) Lentiviral Particles - sc-93182-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NAGPA RNAi - H00051172-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN14933 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14933 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04950 from Sigma-Aldrich

Category miRNA

NAGPA siRNA (Human) - CRH9581 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NAGPA (NM_016256.3) - SHH349056 from Creative biogene

Category siRNA
Species Reactivities Human

Human NAGPA siRNA - orb270083 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NAGPA shRNA Plasmid (Human) - CHH9581 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NAGPA miRNA 3'UTR clone - MiUTR3H-09634 from Creative biogene

Species Reactivities Human
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