Gene Symbol | LY75 |
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Entrez Gene | 4065 |
Alt Symbol | CD205, CLEC13B, DEC-205, GP200-MR6, LY-75 |
Species | Human |
Gene Type | protein-coding |
Description | lymphocyte antigen 75 |
Other Description | C-type lectin domain family 13 member B |
Swissprots | Q53TF5 Q53R46 O60449 Q7Z575 O75913 Q7Z577 |
Accessions | AAY14943 AAY24189 CCQ43175 O60449 AA279177 AB208915 BAD92152 AF011333 AAC17636 AF064827 AAC62622 AK310678 AU099700 BC057232 BC172265 AAI72265 DB135177 DB146492 DB150194 NM_002349 NP_002340 |
Function | Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes. {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. {ECO:0000269|PubMed:12824192, ECO:0000269|PubMed:9862343}. |
Human LY75 peptide - ab102607 from Abcam
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DEC-205 / CD205 / LY75 Antibody Blocking Peptide - LS-E9890 from LifeSpan Bioscience
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LY75-Antibody-Center-Blocking-Peptide - BP8994c from Abgent, a WuXi AppTec company
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Human LY75 (His Tag) protein - orb232442 from Biorbyt
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CD205 Blocking Peptide - abx062893 from Abbexa
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Recombinant Human LY75-CD302 - LY75-CD302-1395H from Creative Biomart
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Recombinant Lymphocyte Antigen 75 (LY75) - RPB593Mu01 from Uscn Life Science Inc.
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Recombinant Lymphocyte Antigen 75 (LY75) - RPB593Mu02 from Uscn Life Science Inc.
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CD205 Blocking Peptide - CBP1699 from Cohesion Biosciences
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LY75 Peptide - BS5653P from Bioworld Technology
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CD205 (K499) Peptide - BS9211P from Bioworld Technology
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Recombinant Human Lymphocyte antigen 75(LY75) ,partial - CSB-YP013251HU CSB-EP013251HU CSB-BP013251HU CSB-MP013251HU from Cusabio
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Recombinant Human LY75 Protein, His-tagged - LY75-782H from Creative Biomart
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LY75 Peptide, Human - M34GP09010H from Creative Peptides
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Renal Cell Carcinoma (gp200) Recombinant Protein Antigen - NBP2-48926PEP from Novus Biologicals
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Human LY75 / DEC-205 / CD205 Protein (His Tag) - 16490-H08H from ABclonal
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Renal Cell Carcinoma (gp200) Recombinant Protein Antigen - NBP2-58339PEP from Novus Biologicals
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Lymphocyte Antigen 75, Recombinant Protein - MBS2030438 from MyBioSource
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Lymphocyte antigen 75 (LY75), partial, Recombinant Protein - MBS1093466 from MyBioSource
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LY75 peptide - orb217562 from Biorbyt
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