MRGPRX1

Gene Symbol MRGPRX1
Entrez Gene 259249
Alt Symbol GPCR, MGRG2, MRGX1, SNSR4
Species Human
Gene Type protein-coding
Description MAS-related GPR, member X1
Other Description G protein-coupled receptor MRGX1|G protein-coupled receptor SNSR3|Mas-related G protein-coupled receptor G2|mas-related G-protein coupled receptor member X1|sensory neuron-specific G-protein coupled receptor 3/4
Swissprots Q8TDD9 Q8TDD8 Q4V9L2 Q96LB2
Accessions AAK91804 AAL86880 AAL86881 ACG60652 BAB89341 BAC06064 CDG86188 EAW68360 Q96LB2 BC096835 AAH96835 NM_147199 NP_671732
Function Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in a histamine-independent manner. {ECO:0000269|PubMed:11850634, ECO:0000269|PubMed:20004959}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. {ECO:0000269|PubMed:11850634}.

Anti-MRGX1 antibody - ab77519 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MRGX1 antibody (ab77519) at 1/500 dilutionLane 1 : Extracts from MCF-7 cellsLane 2 : Extracts from MCF-7 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-MRGX1 / MRGPRX1 Antibody (aa14-28) - LS-C122088 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MRGX1 / MRGPRX1 Antibody (aa14-28) - LS-C122087 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MRGX1 / MRGPRX1 Antibody (N-Terminus, Magnetic beads) - LS-C171959 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MRGX1 / MRGPRX1 Antibody (N-Terminus, Sepharose) - LS-C171960 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MRGX1 / MRGPRX1 Antibody (C-Terminus) - LS-C151375 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MRGX1 / MRGPRX1 antibody Western Blot of Fetal Small Intestine.

Anti-MRGX1 / MRGPRX1 Antibody (N-Terminus) - LS-C171958 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MRGX1 / MRGPRX1 Antibody (aa271-320) - LS-C120746 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HepG2 cells, using MRGX1 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-MRGX1 / MRGPRX1 Antibody (N-Terminus) IHC-plus™ - LS-A2756 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MRGPRX1 / MRGX1 antibody LS-A2756 IHC of human ganglion cells and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MRGX1 Antibody - NLS2756 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: MRGX1 Antibody [NLS2756] - Anti-MRGX1 / MRGPRX1 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MRGX1/X3/X4 Antibody - NB110-75034 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MRGPRX1/3/4 Polyclonal Antibody - bs-6606R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Antigen: bs-6606P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;\\nTMB staining;\\nRead the data in MicroplateReader by 450

Anti-MRGPRX1 / MRGX1 antibody produced in rabbit - SAB2900530 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MRGPRX1/MRGX1 (Cytoplasmic Domain), antibody produced in rabbit: <B>Cat. No. SAB2900530</B>: Anti-MRGPRX1/MRGX1 antibody IHC staining of human ganglion cells and Schwann cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-MRGPRX1 antibody produced in rabbit - SAB4301096 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MRGX1, C-Terminal antibody produced in rabbit - SAB4501095 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-MRGX1, C-Terminal: <B>Cat. No. SAB4501095</B>: Immunofluorescence of HepG2 cells using Anti-MRGX1, C-Terminal antibody. Cells on the left were treated with the Anti-MRGX1, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-MRGX1, C-Terminal antibody and the synthesized immunogen peptide.

FZD4 Antibody - C-terminal region (ARP41265_P050) - ARP41265_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MRGPRX1 Antibody - C-terminal region (ARP59925_P050) - ARP59925_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GPCR JEG18 antibody - GTX71069 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-GPCR JEG18 antibody used in Immunohistochemistry. GTX71069

GPCR LS190419 antibody - GTX70831 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal

GPCR LS190419 antibody - GTX70833 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-GPCR LS190419 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX70833

GPCR LS190419 antibody - GTX71329 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal

GPCR LS195564 antibody - GTX71471 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal

GPCR LS195564 antibody - GTX71835 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-GPCR LS195564 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX71835

GPCR MRGX1 antibody - GTX12856 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal

GPCR ORF4 antibody - GTX70601 from GeneTex

Prices $319.00
Sizes 25 μg
Host Rabbit
Clonality Polyclonal
Anti-GPCR ORF4 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX70601
Search more