Gene Symbol | IL1F10 |
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Entrez Gene | 84639 |
Alt Symbol | FIL1-theta, FKSG75, IL-1HY2, IL-38, IL1-theta, IL1HY2 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 1 family, member 10 (theta) |
Other Description | FIL1 theta|IL-1 theta|IL-1F10 (canonical form IL-1F10a)|family of interleukin 1-theta|interleukin-1 HY2|interleukin-1 family member 10|interleukin-1 receptor antagonist FKSG75|interleukin-1 receptor antagonist-like FIL1 theta|interleukin-38 |
Swissprots | Q53SR9 Q7RTZ5 Q9BYX1 Q969H5 Q56AT8 Q8WWZ1 |
Accessions | AAK68049 AAX59032 AAY14991 CAD29878 EAW73619 EAW73620 Q8WWZ1 AF334755 AAK68048 AY026753 AAK01948 AY029413 AAK33010 AY358846 AAQ89205 BC103966 AAI03967 BC103967 AAI03968 BC103968 AAI03969 NM_032556 NP_115945 NM_173161 NP_775184 |
Function | Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. {ECO:0000269|PubMed:22315422}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. |
IL-1F10 (C-15) - sc-168148 from Santa Cruz Biotechnology
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Anti-IL1F10 antibody - C-terminal - ab180898 from Abcam
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Anti-IL1F10 Antibody (C-Terminus) - LS-C201139 from LifeSpan Bioscience
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Anti-IL1F10 Antibody - LS-C70846 from LifeSpan Bioscience
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Anti-IL1F10 Antibody (aa65-114) - LS-C135753 from LifeSpan Bioscience
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IL-38/IL-1F10 Antibody - NBP2-31798 from Novus Biologicals
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IL-38/IL-1F10 Antibody [Unconjugated] - AF2427 from Novus Biologicals
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IL-38/IL-1F10 Antibody (316709) - MAB2427 from Novus Biologicals
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IL-38/IL-1F10 Antibody - NBP1-91501 from Novus Biologicals
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IL-38/IL-1F10 Antibody [Biotin] - BAF2427 from Novus Biologicals
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Anti-IL1F10 (11-25) antibody produced in rabbit - SAB1103096 from Sigma-Aldrich
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Anti-IL1F10 antibody produced in rabbit - HPA059813 from Sigma-Aldrich
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Anti-IL-1F10 antibody produced in rabbit - SAB3501046 from Sigma-Aldrich
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IL1F10 antibody - middle region (ARP60267_P050) - ARP60267_P050 from Aviva Systems Biology
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Human IL-38/IL-1F10 Biotinylated Antibody - BAF2427 from R&D Systems
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Human IL-38/IL-1F10 Antibody - MAB2427 from R&D Systems
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Human IL-38/IL-1F10 MAb (Clone 316709), Rat IgG2B - MAB2427-SP from R&D Systems
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Human IL-38/IL-1F10 Antibody - AF2427 from R&D Systems
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Human IL-38/IL-1F10 Affinity Purified Polyclonal Ab, Goat IgG - AF2427-SP from R&D Systems
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Mouse IL-38/IL-1F10 Antibody - MAB7774 from R&D Systems
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Mouse IL-38/IL-1F10 MAb (Clone 798036), Rat IgG2A - MAB7774-SP from R&D Systems
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Mouse IL-38/IL-1F10 Alexa Fluor® 488-conjugated Antibody - IC7774G from R&D Systems
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IL1F10 antibody - orb184434 from Biorbyt
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IL1F10 antibody - 70R-10020 from Fitzgerald
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IL1F10 / FIL1T antibody - 60319-1-Ig from Acris Antibodies
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