MAX

Gene Symbol	MAX
Entrez Gene	4149
Alt Symbol	bHLHd4
Species	Human
Gene Type	protein-coding
Description	MYC associated factor X
Other Description	class D basic helix-loop-helix protein 4|protein max
Swissprots	A6NH73 P61244 Q14803 Q96CY8 A8K4G4 A8K265 A8K824
Accessions	CAA47337 CAA47338 CAA47339 EAW80898 EAW80899 EAW80900 EAW80901 EAW80902 EAW80903 EAW80904 EAW80905 EAW80906 P61244 AI652319 AI655674 AI769390 AI917842 AI954328 AK290130 BAF82819 AK290929 BAF83618 AK292189 BAF84878 AK292630 BAF85319 AK303412 BAG64465 AL833643 AY353088 AAQ57210 BC003525 AAH03525 BC004516 AAH04516 BC013669 AAH13669 BC025685 AAH25685 BC027924 AAH27924 BC036092 AAH36092 BF038005 BF062526 BG177865 CR542191 CAG46988 DB451269 DB482510 HY018878 JF432558 ADZ15775 M64240 AAA36200 X60287 CAA42827 XM_011536773 XP_011535075 XR_429315 XR_943450 XR_943451 XR_943452 NM_001271068 NP_001257997 NM_001271069 NP_001257998 NM_002382 NP_002373 NM_145112 NP_660087 NM_145113 NP_660088 NM_145114 NP_660089 NM_197957 NP_932061 NR_073137 NR_073138 NM_145116
Function	Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Subcellular Location	Nucleus. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Top Pathways	Small cell lung cancer, MAPK signaling pathway, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MAX-Over-expression-Lysate - LY10774a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

MAX overexpression lysate - LY408020 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MAX 293 Cell Lysate - 404472 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MAX 293 Cell Lysate - 404473 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MAX 293 Cell Lysate - 404474 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Max Overexpression Lysate (Native) - NBL1-12921 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Max Overexpression Lysate (Native) - NBL1-12920 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Max Overexpression Lysate (Native) - NBL1-12919 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Max Overexpression Lysate (Native) - NBP2-05496 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Max (h): 293T Lysate - sc-114184 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Max (h2): 293T Lysate - sc-114229 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

MAX Over-expression Lysate Product - GWB-FCDCA9 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MAX Over-expression Lysate Product - GWB-56E43C from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MAX Over-expression Lysate Product - GWB-2E2D42 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MAX Over-expression Lysate Product - GWB-1E4F8E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human MAX / MYC associated factor X Insect Cell Lysate (WB positive control) - 12885-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human MAX Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175195 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Max Overexpression Lysate (Denatured) - H00004149-T02 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human MAX Knockdown Stable Cell Line - CSC-DC009263 from Creative biogene Category Cell Line Species Human

Human MAX Knockout Cell Line-HEK293T - CSC-RT0940 from Creative biogene Category Cell Line Species Human

MAX KO Cell Lysate-HEK293T - CLKO-0431 from Creative biogene Category Cell Lysate

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