| Gene Symbol | MAX |
|---|---|
| Entrez Gene | 4149 |
| Alt Symbol | bHLHd4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | MYC associated factor X |
| Other Description | class D basic helix-loop-helix protein 4|protein max |
| Swissprots | A6NH73 P61244 Q14803 Q96CY8 A8K4G4 A8K265 A8K824 |
| Accessions | CAA47337 CAA47338 CAA47339 EAW80898 EAW80899 EAW80900 EAW80901 EAW80902 EAW80903 EAW80904 EAW80905 EAW80906 P61244 AI652319 AI655674 AI769390 AI917842 AI954328 AK290130 BAF82819 AK290929 BAF83618 AK292189 BAF84878 AK292630 BAF85319 AK303412 BAG64465 AL833643 AY353088 AAQ57210 BC003525 AAH03525 BC004516 AAH04516 BC013669 AAH13669 BC025685 AAH25685 BC027924 AAH27924 BC036092 AAH36092 BF038005 BF062526 BG177865 CR542191 CAG46988 DB451269 DB482510 HY018878 JF432558 ADZ15775 M64240 AAA36200 X60287 CAA42827 XM_011536773 XP_011535075 XR_429315 XR_943450 XR_943451 XR_943452 NM_001271068 NP_001257997 NM_001271069 NP_001257998 NM_002382 NP_002373 NM_145112 NP_660087 NM_145113 NP_660088 NM_145114 NP_660089 NM_197957 NP_932061 NR_073137 NR_073138 NM_145116 |
| Function | Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. |
| Subcellular Location | Nucleus. Cell projection, dendrite {ECO:0000250}. |
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. |
| Top Pathways | Small cell lung cancer, MAPK signaling pathway, Transcriptional misregulation in cancer |
Human-MAX-cDNA-Clone - DC01506 from Abgent, a WuXi AppTec company
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MAX - MBS1273348 from MyBioSource
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MAX - MBS1275930 from MyBioSource
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MAX - MBS1273380 from MyBioSource
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MAX - MBS1276979 from MyBioSource
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MAX - MBS1273985 from MyBioSource
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Human MAX ORF Clone(NM_197957.3) - CDCR325379 from Creative Biomart
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Human MAX ORF Clone(NM_197957.3) - CDCR325380 from Creative Biomart
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Human MAX ORF Clone(NM_001271068.1) - CDCL169685 from Creative Biomart
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Human MAX ORF Clone(NM_001271068.1) - CDCL169686 from Creative Biomart
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Human MAX ORF Clone(NM_197957.3) - CDCR325379 from Creative biogene
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Human MAX ORF Clone (BC013669) - CDCS410768 from Creative biogene
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Human MAX ORF Clone (BC025685) - CDCS410769 from Creative biogene
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Human MAX ORF Clone (BC036092) - CDCS410770 from Creative biogene
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Human MAX ORF Clone (BC003525) - CDCS410771 from Creative biogene
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Human MAX ORF Clone (BC004516) - CDCS410772 from Creative biogene
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Human MYC associated factor X Gene ORF cDNA clone in cloning vector - HG12885-U from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, C-HA tag - HG12885-CY from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12885-CF from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12885-ACR from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, N-HA tag - HG12885-NY from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG12885-ANR from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12885-NM from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12885-ACG from Sino Biological
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Human MYC associated factor X Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12885-NF from Sino Biological
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