MAX

Gene Symbol	MAX
Entrez Gene	4149
Alt Symbol	bHLHd4
Species	Human
Gene Type	protein-coding
Description	MYC associated factor X
Other Description	class D basic helix-loop-helix protein 4|protein max
Swissprots	A6NH73 P61244 Q14803 Q96CY8 A8K4G4 A8K265 A8K824
Accessions	CAA47337 CAA47338 CAA47339 EAW80898 EAW80899 EAW80900 EAW80901 EAW80902 EAW80903 EAW80904 EAW80905 EAW80906 P61244 AI652319 AI655674 AI769390 AI917842 AI954328 AK290130 BAF82819 AK290929 BAF83618 AK292189 BAF84878 AK292630 BAF85319 AK303412 BAG64465 AL833643 AY353088 AAQ57210 BC003525 AAH03525 BC004516 AAH04516 BC013669 AAH13669 BC025685 AAH25685 BC027924 AAH27924 BC036092 AAH36092 BF038005 BF062526 BG177865 CR542191 CAG46988 DB451269 DB482510 HY018878 JF432558 ADZ15775 M64240 AAA36200 X60287 CAA42827 XM_011536773 XP_011535075 XR_429315 XR_943450 XR_943451 XR_943452 NM_001271068 NP_001257997 NM_001271069 NP_001257998 NM_002382 NP_002373 NM_145112 NP_660087 NM_145113 NP_660088 NM_145114 NP_660089 NM_197957 NP_932061 NR_073137 NR_073138 NM_145116
Function	Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.
Subcellular Location	Nucleus. Cell projection, dendrite {ECO:0000250}.
Tissue Specificity	High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Top Pathways	Small cell lung cancer, MAPK signaling pathway, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAX full length protein - ab95309 from Abcam Category Protein Source E. coli Species Human

Human MAX full length protein - ab82181 from Abcam Category Protein Source E. coli Species Human

Human MAX peptide - ab88162 from Abcam Category Peptide

Human MAX peptide - ab23161 from Abcam Category Peptide Species Human

MAX Antibody Blocking Peptide - LS-E10932 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAX Antibody Blocking Peptide - LS-E25213 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAX Antibody Blocking Peptide - LS-E14465 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAX Antibody Blocking Peptide - LS-E13694 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Max Recombinant Protein - H00004149-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Max Protein - NBP1-44497 from Novus Biologicals Category Protein Species Human

MAX-Antibody-C-term-Y123-Blocking-Peptide - BP18607b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAX blocking peptide - GTX89997-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

MAX Protein (OPPA02331) - OPPA02331 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human MAX protein (GST Tag) - orb139320 from Biorbyt Category Protein Prices $298.00, $434.00 Sizes 20 μg, 50 μg Source Baculovirus-Insect Cells Species Human

Human MAX protein - orb81211 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

Human Max protein - orb49543 from Biorbyt Category Protein Prices $306.00, $680.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

MAX Blocking Peptide - 33R-6408 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MAX Blocking Peptide - 33R-5344 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MAX protein (His tag) - 80R-1304 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

MAX (phospho-Ser11) Blocking Peptide - abx064172 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken

MAX Peptide - AC21-0035-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MAX (1-160, His-tag) - AR09449PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

MAX (1-160, His-tag) - AR09449PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

MAX - H00004149-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAX - H00004149-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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