LAMTOR1

Gene Symbol LAMTOR1
Entrez Gene 55004
Alt Symbol C11orf59, PDRO, Ragulator1, p18, p27RF-Rho
Species Human
Gene Type protein-coding
Description late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Other Description RhoA activator C11orf59|late endosomal/lysosomal adaptor and MAPK and MTOR activator 1|lipid raft adaptor protein p18|p27Kip1-releasing factor from RhoA|p27kip1 releasing factor from RhoA|protein associated with DRMs and endosomes|ragulator complex protein LAMTOR1|ragulator complex protein PDRO
Swissprots Q9NWT0 Q6IAA8 Q8WZ09
Accessions EAW74836 EAW74837 Q6IAA8 AF289583 AAL55767 AK000632 BAA91297 AK300681 BAG62364 BC001706 AAH01706 BX381569 CR457247 CAG33528 NM_017907 NP_060377
Function As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation. {ECO:0000269|PubMed:19654316, ECO:0000269|
Subcellular Location Late endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Cell membrane.

chromosome 11 open reading frame 59, ELISA Kit - MBS9335196 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5.0 pg/ml.
Range 31.2 pg/ml - 1000 pg/ml.

Human LAMTOR1 ELISA Kit - E088783 from Biobool

Category ELISA Kit

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9351197 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9351763 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9344968 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9346362 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9367974 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9345653 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9364757 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9348142 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9349823 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9345630 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9356770 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9348513 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9346046 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9366724 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

LAMTOR1 (Ragulator complex protein LAMTOR1), ELISA Kit - MBS7606237 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/ml
Range 0.313-20ng/ml

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9351313 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9368893 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9377559 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9344835 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9353225 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9345864 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ragulator Complex Protein LAMTOR1 (C11ORF59), ELISA Kit - MBS9366781 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

LAMTOR1 ELISA Kit (Human) (OKWB00202) - OKWB00202 from Aviva Systems Biology

Category ELISA Kit
Sensitivity 0.188 ng/mL
Range 0.313 - 20 ng/mL
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