Gene Symbol | G2E3 |
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Entrez Gene | 55632 |
Alt Symbol | KIAA1333, PHF7B |
Species | Human |
Gene Type | protein-coding |
Description | G2/M-phase specific E3 ubiquitin protein ligase |
Other Description | G2/M phase-specific E3 ubiquitin-protein ligase|G2/M-phase specific E3 ubiquitin ligase|PHD finger protein 7B |
Swissprots | Q9NXC0 Q9BVR2 Q9P2L3 Q9H9E9 Q7L622 |
Accessions | EAW65969 Q7L622 AB037754 BAA92571 AI432917 AK000340 BAA91095 AK022867 BAB14280 AK093536 AK225346 AK295571 BAG58471 AK296872 BAG59435 AW963891 BC000973 AAH00973 BC008436 BC040179 AAH40179 BM993069 DA491192 XM_005267836 XP_005267893 XM_011536925 XP_011535227 XM_011536926 XP_011535228 XM_011536927 XP_011535229 XM_011536928 XP_011535230 XM_011536929 XP_011535231 NM_001308097 NP_001295026 NM_017769 NP_060239 |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. {ECO:0000269|PubMed:18511420}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:17239372}. Cytoplasm {ECO:0000269|PubMed:17239372}. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage. |
Tissue Specificity | Predominantly expressed in brain, liver, kidney, testes and ovary. {ECO:0000269|PubMed:10718198}. |
G2E3 (C-16) - sc-160340 from Santa Cruz Biotechnology
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Anti-KIAA1333 antibody - ab69905 from Abcam
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Anti-G2E3 / KIAA1333 Antibody (aa226-252, APC) - LS-C235487 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252, Biotin) - LS-C235489 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252, AP) - LS-C235488 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252, FITC) - LS-C235490 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252, PE) - LS-C235492 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252, Azide-free, HRP) - LS-C249026 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252) - LS-C321501 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa226-252) - LS-C159694 from LifeSpan Bioscience
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Anti-G2E3 / KIAA1333 Antibody (aa51-100) - LS-C80555 from LifeSpan Bioscience
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G2E3 Antibody - NBP1-82184 from Novus Biologicals
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G2E3 Antibody - NBP1-55281 from Novus Biologicals
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ANTI-G2E3 (CENTER) antibody produced in rabbit - SAB1305845 from Sigma-Aldrich
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Anti-G2E3 antibody produced in rabbit - HPA001601 from Sigma-Aldrich
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Anti-KIAA1333 antibody produced in rabbit - AV43228 from Sigma-Aldrich
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KIAA1333 antibody - N-terminal region (ARP43228_P050) - ARP43228_P050 from Aviva Systems Biology
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G2E3-Antibody-Center - AP18914c from Abgent, a WuXi AppTec company
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KIAA1333 antibody [N1N3] - GTX118233 from GeneTex
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KIAA1333 antibody, N-term - GTX46917 from GeneTex
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G2E3 Antibody - middle region (OAAB14452) - OAAB14452 from Aviva Systems Biology
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KIAA1333 antibody - 70R-3092 from Fitzgerald
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Anti -G2E3, ID (G2E3, KIAA1333, G2/M phase-specific E3 ubiquitin-protein ligase) - 035826 from USBiological Life Science
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Anti -G2E3, ID (G2E3, KIAA1333, G2/M phase-specific E3 ubiquitin-protein ligase) (AP) - 035826-AP from USBiological Life Science
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Anti -G2E3, ID (G2E3, KIAA1333, G2/M phase-specific E3 ubiquitin-protein ligase) (APC) - 035826-APC from USBiological Life Science
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