G2E3

Gene Symbol G2E3
Entrez Gene 55632
Alt Symbol KIAA1333, PHF7B
Species Human
Gene Type protein-coding
Description G2/M-phase specific E3 ubiquitin protein ligase
Other Description G2/M phase-specific E3 ubiquitin-protein ligase|G2/M-phase specific E3 ubiquitin ligase|PHD finger protein 7B
Swissprots Q9NXC0 Q9BVR2 Q9P2L3 Q9H9E9 Q7L622
Accessions EAW65969 Q7L622 AB037754 BAA92571 AI432917 AK000340 BAA91095 AK022867 BAB14280 AK093536 AK225346 AK295571 BAG58471 AK296872 BAG59435 AW963891 BC000973 AAH00973 BC008436 BC040179 AAH40179 BM993069 DA491192 XM_005267836 XP_005267893 XM_011536925 XP_011535227 XM_011536926 XP_011535228 XM_011536927 XP_011535229 XM_011536928 XP_011535230 XM_011536929 XP_011535231 NM_001308097 NP_001295026 NM_017769 NP_060239
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. {ECO:0000269|PubMed:18511420}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:17239372}. Cytoplasm {ECO:0000269|PubMed:17239372}. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage.
Tissue Specificity Predominantly expressed in brain, liver, kidney, testes and ovary. {ECO:0000269|PubMed:10718198}.

Human KIAA1333 protein fragment - ab163156 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163156 on a 12.5% SDS-PAGE stained with Coomassie Blue.

G2E3 / KIAA1333 Antibody Blocking Peptide - LS-E6241 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human G2E3 Protein - H00055632-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

G2E3-Antibody-Center-Blocking-Peptide - BP18914c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

KIAA1333 Blocking Peptide - 33R-4215 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

G2E3 - H00055632-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

G2E3 - H00055632-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

G2E3 fusion protein - ag19532 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase(G2E3) - CSB-YP741972HU CSB-EP741972HU CSB-BP741972HU CSB-MP741972HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

G2E3 Protein - NBP1-82184PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

G2E3 Peptide, Human - M34GP05996H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

G2/M phase-specific E3 ubiquitin-protein ligase (G2E3), Recombinant Protein - MBS1323903 from MyBioSource

Category Protein
Prices $1,515.00, $1,515.00, $1,740.00, $1,740.00, $2,590.00, $2,590.00, $3,035.00, $3,035.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more