Gene Symbol | G2E3 |
---|---|
Entrez Gene | 55632 |
Alt Symbol | KIAA1333, PHF7B |
Species | Human |
Gene Type | protein-coding |
Description | G2/M-phase specific E3 ubiquitin protein ligase |
Other Description | G2/M phase-specific E3 ubiquitin-protein ligase|G2/M-phase specific E3 ubiquitin ligase|PHD finger protein 7B |
Swissprots | Q9NXC0 Q9BVR2 Q9P2L3 Q9H9E9 Q7L622 |
Accessions | EAW65969 Q7L622 AB037754 BAA92571 AI432917 AK000340 BAA91095 AK022867 BAB14280 AK093536 AK225346 AK295571 BAG58471 AK296872 BAG59435 AW963891 BC000973 AAH00973 BC008436 BC040179 AAH40179 BM993069 DA491192 XM_005267836 XP_005267893 XM_011536925 XP_011535227 XM_011536926 XP_011535228 XM_011536927 XP_011535229 XM_011536928 XP_011535230 XM_011536929 XP_011535231 NM_001308097 NP_001295026 NM_017769 NP_060239 |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. {ECO:0000269|PubMed:18511420}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:17239372}. Cytoplasm {ECO:0000269|PubMed:17239372}. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage. |
Tissue Specificity | Predominantly expressed in brain, liver, kidney, testes and ovary. {ECO:0000269|PubMed:10718198}. |
Human KIAA1333 protein fragment - ab163156 from Abcam
|
||||||||||
G2E3 / KIAA1333 Antibody Blocking Peptide - LS-E6241 from LifeSpan Bioscience
|
||||||||||
Recombinant Human G2E3 Protein - H00055632-Q01 from Novus Biologicals
|
||||||||||
G2E3-Antibody-Center-Blocking-Peptide - BP18914c from Abgent, a WuXi AppTec company
|
||||||||||
KIAA1333 Blocking Peptide - 33R-4215 from Fitzgerald
|
||||||||||
G2E3 - H00055632-Q01-10 from Acris Antibodies
|
||||||||||
G2E3 - H00055632-Q01-25 from Acris Antibodies
|
||||||||||
G2E3 fusion protein - ag19532 from Proteintech Group
|
||||||||||
Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase(G2E3) - CSB-YP741972HU CSB-EP741972HU CSB-BP741972HU CSB-MP741972HU from Cusabio
|
||||||||||
G2E3 Protein - NBP1-82184PEP from Novus Biologicals
|
||||||||||
G2E3 Peptide, Human - M34GP05996H from Creative Peptides
|
||||||||||
G2/M phase-specific E3 ubiquitin-protein ligase (G2E3), Recombinant Protein - MBS1323903 from MyBioSource
|