G2E3

Gene Symbol G2E3
Entrez Gene 55632
Alt Symbol KIAA1333, PHF7B
Species Human
Gene Type protein-coding
Description G2/M-phase specific E3 ubiquitin protein ligase
Other Description G2/M phase-specific E3 ubiquitin-protein ligase|G2/M-phase specific E3 ubiquitin ligase|PHD finger protein 7B
Swissprots Q9NXC0 Q9BVR2 Q9P2L3 Q9H9E9 Q7L622
Accessions EAW65969 Q7L622 AB037754 BAA92571 AI432917 AK000340 BAA91095 AK022867 BAB14280 AK093536 AK225346 AK295571 BAG58471 AK296872 BAG59435 AW963891 BC000973 AAH00973 BC008436 BC040179 AAH40179 BM993069 DA491192 XM_005267836 XP_005267893 XM_011536925 XP_011535227 XM_011536926 XP_011535228 XM_011536927 XP_011535229 XM_011536928 XP_011535230 XM_011536929 XP_011535231 NM_001308097 NP_001295026 NM_017769 NP_060239
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. {ECO:0000269|PubMed:18511420}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:17239372}. Cytoplasm {ECO:0000269|PubMed:17239372}. Note=Shuttles between the nucleus and the cytoplasm. In the nucleus, delocalizes from the nucleolus to the nucleoplasm in response to DNA damage.
Tissue Specificity Predominantly expressed in brain, liver, kidney, testes and ovary. {ECO:0000269|PubMed:10718198}.

G2E3 CRISPR/Cas9 KO Plasmid (h) - sc-405720 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 HDR Plasmid (h) - sc-405720-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 Double Nickase Plasmid (h) - sc-405720-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 Double Nickase Plasmid (h2) - sc-405720-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 CRISPR Activation Plasmid (h) - sc-405720-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 CRISPR Activation Plasmid (h2) - sc-405720-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 Lentiviral Activation Particles (h) - sc-405720-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 Lentiviral Activation Particles (h2) - sc-405720-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

G2E3 siRNA (h) - sc-92251 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G2E3 shRNA Plasmid (h) - sc-92251-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G2E3 shRNA (h) Lentiviral Particles - sc-92251-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

G2E3 RNAi - H00055632-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU076281 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9031 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9031 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

G2E3 siRNA (Human) - CRJ0791 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

G2E3 - MBS8204994 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human G2E3 (NM_017769.3) - SHH298193 from Creative biogene

Category siRNA
Species Reactivities Human

Human G2E3 siRNA - orb271292 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

G2E3 shRNA Plasmid (Human) - CHJ0791 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

G2E3 miRNA 3'UTR clone - MiUTR4H-TG03685 from Creative biogene

Species Reactivities Human
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