PAPOLA

Gene Symbol	PAPOLA
Entrez Gene	10914
Alt Symbol	PAP
Species	Human
Gene Type	protein-coding
Description	poly(A) polymerase alpha
Other Description	PAP-alpha|polynucleotide adenylyltransferase alpha
Swissprots	Q9BVU2 Q86TV0 P51003 Q8IYF5 Q86SX4
Accessions	EAW81642 EAW81643 EAW81644 EAW81645 EAW81646 EAW81647 EAW81648 EAW81649 P51003 AA236200 AF002990 AK024849 AK057629 AK097832 AK295020 BAG58079 AK302406 BAG63716 AK302984 BAG64124 AK303402 BAG64456 AK307659 AK307680 AK316168 BAH14539 BC000927 AAH00927 BC015150 BC036014 AAH36014 BX089817 BX161482 CAD61935 BX248301 CAD62628 BX248753 CAD66560 CD655865 DB045100 DB483858 X76770 XM_005267281 XP_005267338 XM_005267282 XP_005267339 NM_001252006 NP_001238935 NM_001252007 NP_001238936 NM_001293627 NP_001280556 NM_001293628 NP_001280557 NM_001293632 NP_001280561 NM_032632 NP_116021
Function	Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
Subcellular Location	Cytoplasm. Nucleus. Note=The 90 kDa form is nuclear while the 100 kDa and the 106 kDa forms are both nuclear and cytoplasmic.
Top Pathways	mRNA surveillance pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PAPOLA full length protein - ab161197 from Abcam Category Protein Source Wheat germ Species Human

PAPOLA Antibody Blocking Peptide - LS-E1158 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PAPOLA Protein - H00010914-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PAP-Antibody-Center-Blocking-peptide - BP11691c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PAPOLA - H00010914-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PAPOLA - H00010914-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human PAPOLA - PAPOLA-759H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Poly(A) polymerase alpha(PAPOLA) - CSB-YP017432HU CSB-EP017432HU CSB-BP017432HU CSB-MP017432HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Poly (A) polymerase alpha (PAPOLA), Recombinant Protein - MBS949518 from MyBioSource Category Protein Prices $1,555.00, $1,555.00, $1,785.00, $1,785.00, $2,680.00, $2,680.00, $3,125.00, $3,125.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PAPOLA Recombinant Protein Antigen - NBP1-87345PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PAPOLA Peptide, Human - M34GP11287H from Creative Peptides Category Peptide Source Synthetic. Species Human

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