PAPOLA

Gene Symbol PAPOLA
Entrez Gene 10914
Alt Symbol PAP
Species Human
Gene Type protein-coding
Description poly(A) polymerase alpha
Other Description PAP-alpha|polynucleotide adenylyltransferase alpha
Swissprots Q9BVU2 Q86TV0 P51003 Q8IYF5 Q86SX4
Accessions EAW81642 EAW81643 EAW81644 EAW81645 EAW81646 EAW81647 EAW81648 EAW81649 P51003 AA236200 AF002990 AK024849 AK057629 AK097832 AK295020 BAG58079 AK302406 BAG63716 AK302984 BAG64124 AK303402 BAG64456 AK307659 AK307680 AK316168 BAH14539 BC000927 AAH00927 BC015150 BC036014 AAH36014 BX089817 BX161482 CAD61935 BX248301 CAD62628 BX248753 CAD66560 CD655865 DB045100 DB483858 X76770 XM_005267281 XP_005267338 XM_005267282 XP_005267339 NM_001252006 NP_001238935 NM_001252007 NP_001238936 NM_001293627 NP_001280556 NM_001293628 NP_001280557 NM_001293632 NP_001280561 NM_032632 NP_116021
Function Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
Subcellular Location Cytoplasm. Nucleus. Note=The 90 kDa form is nuclear while the 100 kDa and the 106 kDa forms are both nuclear and cytoplasmic.
Top Pathways mRNA surveillance pathway

PAP-α CRISPR/Cas9 KO Plasmid (h) - sc-403906 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α HDR Plasmid (h) - sc-403906-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α Double Nickase Plasmid (h) - sc-403906-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α Double Nickase Plasmid (h2) - sc-403906-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α CRISPR Activation Plasmid (h) - sc-403906-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α CRISPR Activation Plasmid (h2) - sc-403906-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α Lentiviral Activation Particles (h) - sc-403906-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α Lentiviral Activation Particles (h2) - sc-403906-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α siRNA (h) - sc-40806 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAP shRNA Plasmid (h) - sc-40806-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAP shRNA (h) Lentiviral Particles - sc-40806-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU038451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16316 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16316 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PAPOLA siRNA (Human) - CRH7442 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PAPOLA RNAi - H00010914-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

PAP-α CRISPR/Cas9 KO Plasmid (h2) - sc-403906-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAP-α HDR Plasmid (h2) - sc-403906-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human PAPOLA (NM_032632.4) - SHH370492 from Creative biogene

Category siRNA
Species Reactivities Human

PAPOLA shRNA Plasmid (Human) - CHH7442 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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