TRIM24

Gene Symbol	TRIM24
Entrez Gene	8805
Alt Symbol	PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
Species	Human
Gene Type	protein-coding
Description	tripartite motif containing 24
Other Description	E3 ubiquitin-protein ligase TRIM24|RING finger protein 82|TIF1-alpha|transcription intermediary factor 1-alpha|transcriptional intermediary factor 1|tripartite motif-containing 24
Swissprots	O95854 A4D1R8 O15164 A4D1R7
Accessions	CAF86917 CBJ56868 EAL24046 EAL24047 EAW83884 EAW83885 EAW83886 O15164 AA844662 AF009353 AAB63585 AF119042 AAD17258 AK075306 BAG52105 AK302679 BAG63911 AK312610 AL360186 BC028689 AAH28689 CB988362 XM_011516650 XP_011514952 NM_003852 NP_003843 NM_015905 NP_056989
Function	Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:21164480}. Cytoplasm {ECO:0000269|PubMed:21164480}. Note=Colocalizes with sites of active transcription. Detected both in nucleus and cytoplasm in some breast cancer samples. Predominantly nuclear.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-TIF1 Alpha/TRIM24 Antibody, Affinity Purified - PLA0147 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Mouse/Human TRIM24 / TIF1 ELISA Kit (Cell-Based ELISA) - LS-F3005 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

TRIM24 (Human) IP-WB Antibody Pair - H00008805-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

tripartite motif-containing 24, ELISA Kit - MBS9338240 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml. Range 0.25 ng/ml - 8 ng/ml.

TRIM24 Colorimetric Cell-Based ELISA - CB5776 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

TRIM24 ELISA Kit - DEIA-XYA1785 from Creative Diagnostics Category ELISA Kit

Human TRIM24 ELISA Kit - E100336 from Biobool Category ELISA Kit

anti-TIF1A / TRIM24 antibody - ARG63588 from Arigo Biolaboratories Category ELISA Kit

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9363804 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9368700 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9366410 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9349754 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9345624 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9345810 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9363188 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9360193 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9366230 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9352156 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9348744 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9347618 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9348611 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9346988 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9360304 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9344307 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcriptional Intermediary Factor 1 Alpha (TIF1A), ELISA Kit - MBS9372909 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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