APOBEC3F

Gene Symbol APOBEC3F
Entrez Gene 200316
Alt Symbol A3F, ARP8, BK150C2.4.MRNA, KA6
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
Other Description DNA dC->dU-editing enzyme APOBEC-3F|apolipoprotein B editing enzyme catalytic polypeptide-like 3F|apolipoprotein B mRNA editing enzyme cytidine deaminase|apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F|induced upon T-cell activation
Swissprots B0QYD4 Q7Z2N5 Q6ICH3 Q45F03 Q7Z2N2 Q8IUX4
Accessions AAZ38720 EAW60288 EAW60289 Q8IUX4 AK294810 BAG57929 BC038808 AAH38808 BE888653 BE892372 BG280786 BG744406 BG758984 BM681311 BQ056344 BQ182066 BQ941658 BX367450 CR456395 CAG30281 CU012953 CAK54384 CU013241 CAK54683 CX165430 DA221480 JF262037 AEA39617 KC329530 AGI04218 U38435 XM_011529994 XP_011528296 NM_001006666 NP_001006667 NM_145298 NP_660341
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double- stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-
Subcellular Location Cytoplasm. Cytoplasm, P-body.
Tissue Specificity Widely expressed. Highly expressed in ovary. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:15152192, ECO:0000269|PubMed:20308164}.

DNA dC->dU-editing enzyme APOBEC-3F (APOBEC3F), Human, ELISA Kit - CSB-EL001925HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F, ELISA Kit - MBS932253 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human APOBEC3F is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 15.6 pg/ml -1000 pg/ml.

Human DNA dC->dU-editing enzyme APOBEC-3F(APOBEC3F) ELISA kit - CSB-EL001925HU from Cusabio

Category ELISA Kit
Sensitivity 3.9 pg/ml
Range 15.6 pg/ml-1000 pg/ml

Human DNA dC->dU-editing enzyme APOBEC-3F (APOBEC3F) ELISA Kit - EKC33483 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 3.9 pg/ml
Range 15.6 pg/ml-1000 pg/ml

Human APOBEC3F ELISA Kit - E003296 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human APOBEC3F is typically less than 3.9 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the

APOBEC3F ELISA Kit (Human) (OKCA01204) - OKCA01204 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 3.9 pg/mL
Range 15.6 - 1,000 pg/mL
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