APOBEC3F

Gene Symbol APOBEC3F
Entrez Gene 200316
Alt Symbol A3F, ARP8, BK150C2.4.MRNA, KA6
Species Human
Gene Type protein-coding
Description apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
Other Description DNA dC->dU-editing enzyme APOBEC-3F|apolipoprotein B editing enzyme catalytic polypeptide-like 3F|apolipoprotein B mRNA editing enzyme cytidine deaminase|apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F|induced upon T-cell activation
Swissprots B0QYD4 Q7Z2N5 Q6ICH3 Q45F03 Q7Z2N2 Q8IUX4
Accessions AAZ38720 EAW60288 EAW60289 Q8IUX4 AK294810 BAG57929 BC038808 AAH38808 BE888653 BE892372 BG280786 BG744406 BG758984 BM681311 BQ056344 BQ182066 BQ941658 BX367450 CR456395 CAG30281 CU012953 CAK54384 CU013241 CAK54683 CX165430 DA221480 JF262037 AEA39617 KC329530 AGI04218 U38435 XM_011529994 XP_011528296 NM_001006666 NP_001006667 NM_145298 NP_660341
Function DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double- stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-
Subcellular Location Cytoplasm. Cytoplasm, P-body.
Tissue Specificity Widely expressed. Highly expressed in ovary. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:15152192, ECO:0000269|PubMed:20308164}.

APOBEC3F CRISPR/Cas9 KO Plasmid (h) - sc-406610 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F HDR Plasmid (h) - sc-406610-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F Double Nickase Plasmid (h) - sc-406610-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F Double Nickase Plasmid (h2) - sc-406610-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F CRISPR Activation Plasmid (h) - sc-406610-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F CRISPR Activation Plasmid (h2) - sc-406610-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F Lentiviral Activation Particles (h) - sc-406610-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F Lentiviral Activation Particles (h2) - sc-406610-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APOBEC3F siRNA (h) - sc-60072 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APOBEC3F shRNA Plasmid (h) - sc-60072-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APOBEC3F shRNA (h) Lentiviral Particles - sc-60072-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APOBEC3F RNAi - H00200316-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU095321 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3338 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3338 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

APOBEC3F siRNA (Human) - CRJ6246 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APOBEC3F RNAi - H00200316-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

APOBEC3F - MBS8224142 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APOBEC3F (NM_145298.5) - SHH238446 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human APOBEC3F(NM_001006666.1) - SHG065449 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human APOBEC3F(NM_145298.5) - SHG065485 from Creative biogene

Category siRNA
Species Reactivities Human

Human APOBEC3F siRNA - orb276747 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APOBEC3F shRNA Plasmid (Human) - CHJ6246 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APOBEC3F miRNA 3'UTR clone - MiUTR1H-00474 from Creative biogene

Species Reactivities Human

APOBEC3F miRNA 3'UTR clone - MiUTR1H-00475 from Creative biogene

Species Reactivities Human
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