APOBEC3F

Gene Symbol	APOBEC3F
Entrez Gene	200316
Alt Symbol	A3F, ARP8, BK150C2.4.MRNA, KA6
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
Other Description	DNA dC->dU-editing enzyme APOBEC-3F|apolipoprotein B editing enzyme catalytic polypeptide-like 3F|apolipoprotein B mRNA editing enzyme cytidine deaminase|apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F|induced upon T-cell activation
Swissprots	B0QYD4 Q7Z2N5 Q6ICH3 Q45F03 Q7Z2N2 Q8IUX4
Accessions	AAZ38720 EAW60288 EAW60289 Q8IUX4 AK294810 BAG57929 BC038808 AAH38808 BE888653 BE892372 BG280786 BG744406 BG758984 BM681311 BQ056344 BQ182066 BQ941658 BX367450 CR456395 CAG30281 CU012953 CAK54384 CU013241 CAK54683 CX165430 DA221480 JF262037 AEA39617 KC329530 AGI04218 U38435 XM_011529994 XP_011528296 NM_001006666 NP_001006667 NM_145298 NP_660341
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double- stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-
Subcellular Location	Cytoplasm. Cytoplasm, P-body.
Tissue Specificity	Widely expressed. Highly expressed in ovary. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:15152192, ECO:0000269|PubMed:20308164}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human APOBEC3F full length protein - ab132966 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human APOBEC3F protein fragment - ab165861 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

APOBEC3F / ARP8 Antibody Blocking Peptide - LS-E14657 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOBEC3F / ARP8 Antibody Blocking Peptide - LS-E14656 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOBEC3F / ARP8 Antibody Blocking Peptide - LS-E9985 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APOBEC3F / ARP8 Antibody Blocking Peptide - LS-E15109 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human APOBEC3F Protein - H00200316-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human APOBEC3F Protein - H00200316-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

APOBEC3F-Antibody-N-term-Blocking-Peptide - BP9176a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ApoBEC3F Blocking Peptide - 33R-6629 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ApoBEC3F Blocking Peptide - 33R-6157 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ApoBEC3F Blocking Peptide - 33R-1538 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

APOBEC3F - H00200316-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

APOBEC3F - H00200316-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

APOBEC3F - H00200316-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

APOBEC3F - H00200316-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human DNA dC->dU-editing enzyme APOBEC-3F(APOBEC3F) - CSB-YP816878HU CSB-EP816878HU CSB-BP816878HU CSB-MP816878HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

APOBEC3F Protein - abx163678 from Abbexa Category Protein Species Human

APOBEC3F (transcript variant 1) - TP307845 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

APOBEC3F Peptide, Human - M34GP00778H from Creative Peptides Category Peptide Source Synthetic. Species Human

DNA dC->dU-editing enzyme APOBEC-3F (APOBEC3F), Recombinant Protein - MBS1312704 from MyBioSource Category Protein Prices $1,140.00, $1,140.00, $1,370.00, $1,370.00, $1,815.00, $1,815.00, $2,280.00, $2,280.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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