APOBEC3F

Gene Symbol	APOBEC3F
Entrez Gene	200316
Alt Symbol	A3F, ARP8, BK150C2.4.MRNA, KA6
Species	Human
Gene Type	protein-coding
Description	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
Other Description	DNA dC->dU-editing enzyme APOBEC-3F|apolipoprotein B editing enzyme catalytic polypeptide-like 3F|apolipoprotein B mRNA editing enzyme cytidine deaminase|apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F|induced upon T-cell activation
Swissprots	B0QYD4 Q7Z2N5 Q6ICH3 Q45F03 Q7Z2N2 Q8IUX4
Accessions	AAZ38720 EAW60288 EAW60289 Q8IUX4 AK294810 BAG57929 BC038808 AAH38808 BE888653 BE892372 BG280786 BG744406 BG758984 BM681311 BQ056344 BQ182066 BQ941658 BX367450 CR456395 CAG30281 CU012953 CAK54384 CU013241 CAK54683 CX165430 DA221480 JF262037 AEA39617 KC329530 AGI04218 U38435 XM_011529994 XP_011528296 NM_001006666 NP_001006667 NM_145298 NP_660341
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination- independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double- stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-
Subcellular Location	Cytoplasm. Cytoplasm, P-body.
Tissue Specificity	Widely expressed. Highly expressed in ovary. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:15152192, ECO:0000269|PubMed:20308164}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

APOBEC3F/G (H-55) - sc-367881 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-APOBEC3F antibody - ab87577 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3G antibody - ab194581 from Abcam Prices $384.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-APOBEC3G antibody - ab109727 from Abcam Prices $376.00 Sizes 50 µg Host Goat Clonality Polyclonal

Anti-APOBEC3G antibody - ab172694 from Abcam Prices $376.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-APOBEC3G antibody - ab194955 from Abcam Prices $376.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-APOBEC3G antibody - ab135120 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3G antibody [EPR11660] - ab178701 from Abcam Host Rabbit Clonality Monoclonal Clone EPR11660

Anti-APOBEC3G antibody [mAbcam75560] - ab75560 from Abcam Prices $376.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone mAbcam75560

Anti-APOBEC3G antibody - C-terminal - ab71634 from Abcam Prices $379.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48, AP) - LS-C212764 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48, APC) - LS-C212765 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48, Biotin) - LS-C212766 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48, FITC) - LS-C212767 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48, Azide-free, HRP) - LS-C212769 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48, PE) - LS-C212770 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa28-57) - LS-C319544 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody - LS-C341746 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (C-Terminus) - LS-C82441 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (N-Terminus) - LS-C110500 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (N-Terminus) - LS-C82429 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody (aa22-48) - LS-C156418 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-APOBEC3F / ARP8 Antibody - LS-C155537 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

APOBEC3F Antibody - NBP2-15426 from Novus Biologicals Prices $349.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

APOBEC3F Antibody - NBP1-57372 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

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