Casp3

Gene Symbol	Casp3
Entrez Gene	25402
Alt Symbol	Lice
Species	Rat
Gene Type	protein-coding
Description	caspase 3
Other Description	CASP-3|CPP-32|CPP32beta|Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease)|Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease)|IRP|SCA-1|SREBP cleavage activity 1|apopain|caspase-3|cysteine protease CPP32|protein Yama|yama protein
Swissprots	Q62993 P70543 P97699 P55213
Accessions	EDL78892 EDL78893 EDL78894 P55213 BC081854 AAH81854 U34685 AAC52261 U49930 AAC52765 U84410 AAB41792 XM_006253130 XP_006253192 NM_012922 NP_037054
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Expressed in heart, brain, liver, and muscle but not in kidney or testis.
Top Pathways	Toxoplasmosis, TNF signaling pathway, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Active caspase-3, Rat, ELISA Kit - E02A0015 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Caspase 3, Casp-3, Rat, ELISA Kit - CSB-E08857r from ARP American Research Products Category ELISA Kit Prices $465.00, $615.00, $616.00, $619.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Caspase 3, Rat, ELISA Kit - E02C0549 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Caspase-3, Casp3, Rat, ELISA Kit - E0626r from ARP American Research Products Category ELISA Kit Prices $496.00 Sizes 96 t Range 0.312-20 ng/mL

Caspase-3, Rat, ELISA Kit - E02C0094 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 2.5-50ng/mL,

Rat Caspase-3/CPP32 ELISA Kit - RC0698 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat Caspase-3 ELISA Kit - RC0556 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Rat CASP3(Caspase 3) ELISA Kit - E-EL-R0160 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

Rat CASP3 (Caspase 3) CLIA Kit - E-CL-R0117 from Elabscience Category CLIA Kit Sensitivity 37.50 pg/mL Range Average Recovery (%)

Active caspase-3, ELISA Kit - MBS7244630 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Rat Caspase 3,Casp-3 ELISA Kit - CSB-E08857r from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Rat Caspase 3 ELISA - E02C0549 from BlueGene Biotech Category ELISA Kit

Rat Caspase 3 (CASP3) ELISA Kit - EKU02991 from Biomatik Category ELISA Kit Prices $718.00, $3,196.00, $5,817.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.059 ng/mL Range 0.156-10 ng/mL

Rat CASP3(Caspase 3) ELISA Kit - E-EL-R0160 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.19 ng/mL Range 0.31~20 ng/mL

Rat CASP3 (Caspase 3) CLIA Kit - E-CL-R0117 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.188ng/mL Range 0.313-20ng/mL

Rat SP-A (Pulmonary Surfatcant-Associated Protein A) CLIA Kit - E-CL-R0049 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Rat Caspase 3 ELISA Kit - abx155304 from Abbexa Category ELISA Kit Range 15.63 pg/ml - 1000 pg/ml

Rat Caspase 3 ELISA Kit - abx051512 from Abbexa Category ELISA Kit Sensitivity 0.01 ng/ml Range 0.06 ng/ml - 4 ng/ml

Rat Caspase-3 ELISA Kit - abx256098 from Abbexa Category ELISA Kit Range 0.313 ng/ml - 20 ng/ml

Caspase 3 (CASP3), Rat, ELISA Kit - DL-CASP3-Ra from ARP American Research Products Category ELISA Kit Prices $715.00 Sizes 96 t Range 1.56-100 ng/mL

Rat CASP3 ELISA Kit - abx573766 from Abbexa Category ELISA Kit Sensitivity 0.49 ng/ml Range 1.563 ng/ml - 100 ng/ml

Rat Caspase-3 ELISA Kit - EKE51547 from Biomatik Category ELISA Kit Prices $570.40, $2,424.20, $4,563.20 Sizes 96 t, 5x96t, 10x96t Range 0.312-20 ng/mL

Casp3 - EKR0286 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.313-20ng/ml

Casp3 - EKR286 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.313-20ng/ml

Casp3 ELISA Kit (Rat) : 96 Wells (OKEH02671) - OKEH02671 from Aviva Systems Biology Category ELISA Kit Prices $360.00 Sizes 96 wells Sensitivity < 0.078 ng/mL Range 0.312 - 20 ng/mL

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