Casp3

Gene Symbol	Casp3
Entrez Gene	25402
Alt Symbol	Lice
Species	Rat
Gene Type	protein-coding
Description	caspase 3
Other Description	CASP-3|CPP-32|CPP32beta|Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease)|Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease)|IRP|SCA-1|SREBP cleavage activity 1|apopain|caspase-3|cysteine protease CPP32|protein Yama|yama protein
Swissprots	Q62993 P70543 P97699 P55213
Accessions	EDL78892 EDL78893 EDL78894 P55213 BC081854 AAH81854 U34685 AAC52261 U49930 AAC52765 U84410 AAB41792 XM_006253130 XP_006253192 NM_012922 NP_037054
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Expressed in heart, brain, liver, and muscle but not in kidney or testis.
Top Pathways	Toxoplasmosis, TNF signaling pathway, MicroRNAs in cancer, Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Caspase-3 Protein - NBP1-99209 from Novus Biologicals Category Protein Species Rat

Caspase-3 Protein - NBP1-99594 from Novus Biologicals Category Protein Prices $429.00 Sizes 100 tests Species Rat

Caspase 3 (active) recombinant protein - GTX65329 from GeneTex Category Protein Prices $319.00 Sizes 100 unit Source E. coli Species Rat

Caspase 3 (active) recombinant protein - GTX65509 from GeneTex Category Protein Prices $319.00 Sizes 100 unit Source E. coli Species Rat

Caspase 3 (active) recombinant protein - GTX65330 from GeneTex Category Protein Prices $199.00 Sizes 25 unit Source E. coli Species Rat

Caspase 3 (active) recombinant protein - GTX65510 from GeneTex Category Protein Prices $199.00 Sizes 25 unit Source E. coli Species Rat

Rat Caspase 3 Protein - abx065760 from Abbexa Category Protein Source E.coli Species Rat

Rat Caspase 3 Protein - abx065761 from Abbexa Category Protein Source E.coli Species Rat

Caspase-3 - P5129 from Acris Antibodies Category Protein Prices $430.00 Sizes 25 u Species Rat

Caspase 3 (CASP3), Rat - 20-6906 from ARP American Research Products Category Protein Prices $549.00 Sizes 50 µg Source E.coli Species Rat

Caspase 3 (CASP3), Rat - 20-6907 from ARP American Research Products Category Protein Prices $549.00 Sizes 50 µg Source E.coli Species Rat

Recombinant Rat Caspase 3 - Casp3-1644R from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Rat Caspase 3, His-tagged - Casp3-748R from Creative Biomart Category Protein Source E.coli.

Recombinant Rat Caspase-3(Casp3) - CSB-YP004548RA CSB-EP004548RA CSB-BP004548RA CSB-MP004548RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

Caspase-3, rat recombinant - 1283-100 from Biovision Category Protein Prices $285.00 Sizes 100 units Source E. coli Species Rat

Caspase-3, rat recombinant - 1283-25 from Biovision Category Protein Prices $145.00 Sizes 25 units Source E. coli Species Rat

Caspase 3 (CASP3) - RPU140669 from Biomatik Category Protein Prices $264.00, $528.00, $792.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Rat

Caspase 3 (CASP3) - RPU140670 from Biomatik Category Protein Prices $264.00, $528.00, $792.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Rat

Caspase 3 (CASP3), Recombinant Protein - MBS2010180 from MyBioSource Category Protein Prices $200.00, $430.00, $665.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Caspase 3 (CASP3), Recombinant Protein - MBS2011059 from MyBioSource Category Protein Prices $200.00, $430.00, $665.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

Caspase-3 (Casp3), Recombinant Protein - MBS1206562 from MyBioSource Category Protein Prices $885.00, $885.00, $1,110.00, $1,110.00, $1,300.00, $1,300.00, $1,755.00, $1,755.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

Recombinant Rat CASP3 Protein - CASP3-1145R from Creative Biomart Category Protein Source Mammalian Cells Species Rat

Recombinant Caspase 3 (CASP3) - RPU40669 from Biomatik Category Protein Prices $211.00, $413.00, $660.00, $787.20 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Rat

Recombinant Caspase 3 (CASP3) - RPU40670 from Biomatik Category Protein Prices $211.00, $413.00, $660.00, $787.20 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Rat

CASP3 Recombinant Protein (OPCD01885) - OPCD01885 from Aviva Systems Biology Category Protein Source E.coli Species Rat

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