BNIP3L

Gene Symbol BNIP3L
Entrez Gene 665
Alt Symbol BNIP3a, NIX
Species Human
Gene Type protein-coding
Description BCL2/adenovirus E1B 19kDa interacting protein 3-like
Other Description BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like|BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A|BCL2/adenovirus E1B 19-kd protein-interacting protein 3a|NIP3-like protein X|NIP3L|adenovirus E1B19k-binding protein B5
Swissprots B0AZS9 O60238 Q8NF87 Q5JW63
Accessions AAF70290 EAW63576 O60238 AA946755 AB004788 BAA28692 AF060922 AAG43134 AF067396 AAD03589 AF079221 AAC27723 AF452712 AAL50978 AF536326 AAN04051 AK290213 BAF82902 AK300286 BAG62043 AK300727 BAG62400 AK307195 AK315870 BAF98761 AK316315 BAH14686 AL132665 CAI46217 BC001559 AAH01559 BC009603 AAH09603 BF337139 BQ719112 BT019500 AAV38307 BT019501 AAV38308 CD244492 CD558918 CR456701 CAG32982 EU831983 ACE87424 EU832076 ACE86738 JF432628 ADZ15845 XM_005273617 XP_005273674 XM_011544630 XP_011542932 NM_004331 NP_004322
Function Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. {ECO:0000269|PubMed:10381623, ECO:0000269|PubMed:21264228}.
Subcellular Location Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Colocalizes with SPATA18 at the mitochondrion outer membrane.

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L), Human, ELISA Kit - CSB-EL002767HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L), Human, ELISA Kit - E01B0820 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 0.5-10ng/ml

BNIP3L (Human) IP-WB Antibody Pair - H00000665-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

BCL2/adenovirus E1B 19kDa interacting protein 3-like, ELISA Kit - MBS903923 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human BNIP3L is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 0.312 ng/ml -20 ng/ml.

Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like(BNIP3L) ELISA kit - CSB-EL002767HU from Cusabio

Category ELISA Kit
Sensitivity 0.078 ng/ml.
Range 0.312 ng/ml-20 ng/ml

Human BNIP3L ELISA Kit - E004579 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human BNIP3L is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the

anti-Bnip3L antibody - ARG54385 from Arigo Biolaboratories

Category ELISA Kit

anti-Bnip3L antibody - ARG52571 from Arigo Biolaboratories

Category ELISA Kit

anti-Bnip3L antibody (Ready-to-Use) - ARG52572 from Arigo Biolaboratories

Category ELISA Kit

BNIP3L ELISA Kit (Human) (OKCA01121) - OKCA01121 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 0.078 ng/mL
Range 0.312 - 20 ng/mL

BCL2/Adenovirus E1B 19kDa Protein-Interacting Protein 3-Like (BNIP3L), ELISA Kit - MBS9398671 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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