SPAG9

Gene Symbol SPAG9
Entrez Gene 9043
Alt Symbol CT89, HLC-6, HLC4, HLC6, JIP-4, JIP4, JLP, PHET, PIG6
Species Human
Gene Type protein-coding
Description sperm associated antigen 9
Other Description C-Jun-amino-terminal kinase-interacting protein 4|JNK interacting protein|JNK/SAPK-associated protein|Max-binding protein|c-Jun NH2-terminal kinase-associated leucine zipper protein|cancer/testis antigen 89|human lung cancer oncogene 6 protein|lung cancer oncogene 4|mitogen-activated protein kinase 8-interacting protein 4|proliferation-inducing gene 6|protein highly expressed in testis|sperm associated antigen 9 variant 5|sperm surface protein|sunday driver 1
Swissprots Q8IZX7 Q3KQU8 Q96II0 Q86WC8 Q9H811 O60905 B4DHH2 Q3MKM7 A8MSX0 O60271 A6H8U5 Q86WC7
Accessions EAW94569 EAW94570 EAW94571 EAW94572 EAW94573 EAW94574 O60271 AB011088 BAA25442 AF327452 AAN61565 AF542172 AAQ11383 AK023512 BAG51202 AK024068 BAB14812 AK091921 AK129652 AK295098 BAG58134 AK299553 BAG61498 AK302789 BAG63993 AK307793 AK309214 AY219897 AAO66462 AY219898 AAO66463 AY236487 AAP74807 AY850123 AAX47276 BC007524 AAH07524 BC059946 AAH59946 BC146755 AAI46756 BC153878 AAI53879 DA631864 DC332810 JF432576 ADZ15793 KJ624756 AIC73822 X91879 CAA62987 XM_005257767 XP_005257824 XM_005257768 XP_005257825 XM_005257769 XP_005257826 XM_005257770 XP_005257827 XM_005257771 XP_005257828 XM_005257772 XP_005257829 XM_005257773 XP_005257830 XM_005257774 XP_005257831 XM_006722163 XP_006722226 NM_001130527 NP_001123999 NM_001130528 NP_001124000 NM_001251971 NP_001238900 NM_003971 NP_003962 NM_172345
Function The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg- interaction. {ECO:0000269|PubMed:14743216, ECO:0000269|PubMed:15693750}.
Subcellular Location Cytoplasm. Cytoplasm, perinuclear region. Note=Perinuclear distribution in response to stress signals such as UV radiation.
Tissue Specificity Isoform 5 is expressed only in testis on the round spermatids of stage I, II and II. Isoform 5 is absent in spermatogonia and spermatocyte. Isoform 3 is expressed in testis. Isoform 4 is expressed in testis and in acute myeloid leukemia (AML) patients. {ECO:0000269|PubMed:14662895, ECO:0000269|PubMed:16112646, ECO:0000269|PubMed:9480848}.

JIP4/SPAG9 (D72F4) XP ® Rabbit mAb - 5519 from Cell Signaling Technology

Prices $277.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D72F4
Western blot analysis of extracts from various tissues and cell lines using JIP4/SPAG9 (D72F4) XP ® Rabbit mAb.

JIP-4 (E-20) - sc-67648 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

JIP-4 (H-8) - sc-271492 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JIP-4 (H-8): sc-271492. Western blot analysis of JIP-4 expression in 293T whole cell lysate.

JIP-4 (H-165) - sc-134972 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
JIP-4 (H-165): sc-134972. Western blot analysis of JIP-4 expression in HeLa (A) and AML-193 (B) whole cell lysates.

JIP-4 (F-14) - sc-67649 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JIP-4 (F-14): sc-67649. Western blot analysis of JIP-4 expression in HeLa (A) and AML-193 (B) whole cell lysates.

Anti-JLP antibody - ab12331 from Abcam

Prices $380.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis (left) and testicular seminoma (right) tissues labelling JLP with ab12331 at 1/5000 (0.2µg/ml) and 1/1000 (1µg/ml). Detection: DAB.

Anti-JLP antibody - ab12332 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testicular seminoma tissue labelling JLP with ab12332 at 1/1000 (1µg/ml). Detection: DAB.

Anti-JLP antibody - ab71551 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SPAG9 Antibody (aa91-120) - LS-C100866 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with SPAG9 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-SPAG9 Antibody (aa1-50) IHC-plus™ - LS-B11294 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SPAG9 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11294 concentration 5 ug/ml.

Anti-SPAG9 Antibody (aa775-825) IHC-plus™ - LS-B11295 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SPAG9 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11295 concentration 5 ug/ml.

Anti-SPAG9 Antibody - LS-C190214 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SPAG9 Antibody (Internal) - LS-C153471 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPAG9 Antibody - LS-C342153 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SPAG9 Antibody (aa603-632) - LS-C100867 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with SPAG9 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

SPAG9 Antibody - NBP1-85393 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SPAG9 Antibody [NBP1-85393] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol & microtubule organizing center.

SPAG9 Antibody - NB100-79794 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SPAG9 Antibody [NB100-79794] - Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-JLP used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

SPAG9 Antibody - NB100-79793 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPAG9 Antibody [NB100-79793] - Nuclear extract (NE, 20 ug) from HeLa cells. Antibody used at 0.3 ug/ml.

SPAG9 Antibody - NBP1-31153 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SPAG9 Antibody [NBP1-31153] - Sample (30 ug of whole cell lysate) A: H1299 7. 5% SDS PAGE; antibody diluted at 1:1000.

JLP/JIP-4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12270R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

JLP/JIP-4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12270R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

JLP/JIP-4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12270R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

JLP/JIP-4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12270R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

JLP/JIP-4 Polyclonal Antibody, Cy3 Conjugated - bs-12270R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

JLP/JIP-4 Polyclonal Antibody, Cy5 Conjugated - bs-12270R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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