Ccnd2

Gene Symbol	Ccnd2
Entrez Gene	12444
Alt Symbol	2600016F06Rik, AI256817, BF642806, C86853, Vin-1, Vin1, cD2
Species	Mouse
Gene Type	protein-coding
Description	cyclin D2
Other Description	G1/S-specific cyclin-D2
Swissprots	P30280
Accessions	EDK99856 P30280 AK007904 BAB25338 AK009602 AK011225 AK011412 AK011429 AK077367 AK147345 BAE27858 AK160751 BAE35987 AK168954 BAE40760 AK182883 AK184705 AK185924 AK192301 AK193960 AK199582 AK202387 AK218587 BC049086 AAH49086 BY161742 CT010207 CAJ18415 M83749 AAA37519 M86182 AAA37503 XM_006505459 XP_006505522 XM_006505460 XP_006505523 NM_009829 NP_033959
Function	Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members. {ECO:0000250}.
Top Pathways	PI3K-Akt signaling pathway, Cell cycle, p53 signaling pathway, Focal adhesion, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Cyclin D2, Mouse, ELISA Kit - E03C0484 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10 ng/mL,

G1/S-specific cyclin-D2 (CCND2), Mouse, ELISA Kit - E03G0401 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

G1/S-specific cyclin-D2, Ccnd2, Mouse, ELISA Kit - E0586m from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

Mouse CCND2 ELISA Kit - MC0491 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse CCND2(Cyclin D2) ELISA Kit - E-EL-M0382 from Elabscience Category ELISA Kit Sensitivity 23.44 pg/mL Range 39.06—2500 pg/mL

Mouse CCND2 (Cyclin-D2) CLIA Kit - E-CL-M0245 from Elabscience Category CLIA Kit Sensitivity 7.50 pg/mL Range Average Recovery (%)

CCND2, ELISA Kit - MBS2508349 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

CCND2, ELISA Kit - MBS2511955 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

CCND2, ELISA Kit - MBS2504348 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

CCND2, ELISA Kit - MBS2509728 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25--2000pg/mL

CCND2, ELISA Kit - MBS2510780 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

CCND2, ELISA Kit - MBS2507468 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

CCND2, ELISA Kit - MBS2510030 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

CCND2, ELISA Kit - MBS2502902 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 23.438pg/mL Range 39.063--2500pg/mL

Cyclin D2, ELISA Kit - MBS016385 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS054561 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS028490 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS015693 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS031360 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS021639 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS032905 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 5.0pg/ml. Range 31.2pg/ml-1000pg/ml.

Cyclin D2, ELISA Kit - MBS023958 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS035737 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS073626 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cyclin D2, ELISA Kit - MBS011932 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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