HEY2

Gene Symbol	HEY2
Entrez Gene	23493
Alt Symbol	CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32
Species	Human
Gene Type	protein-coding
Description	hes-related family bHLH transcription factor with YRPW motif 2
Other Description	HES-related repressor protein 1\|HES-related repressor protein 2\|HESR-2\|HRT-2\|cardiovascular basic helix-loop-helix factor 1\|cardiovascular helix-loop-helix factor 1\|class B basic helix-loop-helix protein 32\|hCHF1\|hHRT2\|hairy and enhancer of split-related protein 2\|hairy-related transcription factor 2\|hairy/enhancer-of-split related with YRPW motif 2\|hairy/enhancer-of-split related with YRPW motif protein 2\|protein gridlock homolog
Swissprots	Q9UBP5
Accessions	EAW48135 Q9UBP5 AB044755 BAA96781 AF173901 AAF20173 AF232238 AAF37296 AF237949 AAF44781 AF311884 AAG31157 AJ249545 CAB56839 AK289943 BAF82632 AK303890 BAG64825 BC007707 AAH07707 BI549391 BT020067 AAV38870 BT020068 AAV38871 XM_005266878 XP_005266935 XM_011535649 XP_011533951 XM_011535650 XP_011533952 NM_012259 NP_036391
Function	Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000269\|PubMed:10692439, ECO:0000269\|PubMed:11095750, ECO:0000269\|PubMed:15485867, ECO:0000269\|PubMed:16293227}.
Subcellular Location	Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00380, ECO:0000255\|PROSITE-ProRule:PRU00981}.

HRT2 (A-20) - sc-16446 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

HRT2 (A-20): sc-16446. Western blot analysis of HRT2 expression in human testis tissue extract (A) and Hep G2 nuclear extract (B).

HRT2 (H-95) - sc-28747 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Anti-HEY2 antibody - ab25404 from Abcam

Prices	$378.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-HEY2 antibody (ab25404) at 2 µg/mlLane 1 : Heart (Mouse)Tissue Lysate Lane 2 : Skeletal Muscle (Mouse) Tissue LysateLysates/proteins at 20 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-HEY2 antibody - ab86010 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-HEY2 antibody (ab86010) at 1/1000 dilutionLane 1 : Uninduced cultureLane 2 : Induced culture of E.coli Secondaryanti-Rabbit IgG HRP at 1/1000 dilution

Anti-HEY2 antibody - ab167280 from Abcam

Prices	$376.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-HEY2 antibody (ab167280) at 1 µg/mlLane 1 : HEY2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgG HRP at 1/2500 dilution

Anti-HEY2 antibody - ab70133 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-HEY2 antibody (ab70133) at 1/500 dilutionLane 1 : K562 cell extractsLane 2 : K562 cell extracts with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-HEY2 antibody - ab106235 from Abcam

Prices	$368.00
Sizes	200 µl
Host	Goat
Clonality	Polyclonal

Anti-HEY2 antibody - N-terminal - ab184642 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-HEY2 antibody - N-terminal (ab184642) at 1/1000 dilutionLane 1 : A549 whole cell lysate/extractLane 2 : H1299 whole cell lysate/extractLane 3 : HCT116 whole cell lysate/extractLane 4 : MCF7 whole cell lysate/extractLysates/proteins at 30 µg per lane.

Anti-CHF1 / HEY2 Antibody (aa72-99, Azide-free, HRP) - LS-C249183 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa72-99, PE) - LS-C236201 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (C-Terminus) - LS-C110340 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

HEY2 antibody LS-C110340 Western blot of NCI-H226 cell lysate.

Anti-CHF1 / HEY2 Antibody - LS-C308226 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa72-99) - LS-C321933 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa21-70) - LS-C119299 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from K562 cells, using HEY2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CHF1 / HEY2 Antibody (aa72-99) - LS-C166848 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

HEY2 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CHF1 / HEY2 Antibody (aa295-322) - LS-C203959 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

DANRE hey2 Antibody western blot of zebra fish brain tissue lysates (35 ug/lane). The DANRE hey2 antibody detected the DANRE hey2 protein (arrow).

Anti-CHF1 / HEY2 Antibody (aa314-330) - LS-C7393 from LifeSpan Bioscience

Prices	$475.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (Internal) - LS-C139592 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa72-99, AP) - LS-C236195 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa72-99, APC) - LS-C236196 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa72-99, FITC) - LS-C236199 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CHF1 / HEY2 Antibody (aa72-99, Biotin) - LS-C236197 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

HEY2 Antibody - NBP1-88629 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: HEY2 Antibody [NBP1-88629] - Analysis in control (vector only transfected HEK293T lysate) and hEY2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

HEY2 Antibody - NBP1-52173 from Novus Biologicals

Prices	$229.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

HEY2 Antibody - H00023493-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: HEY2 Antibody [H00023493-B01P] - Analysis of HEY2 expression in transfected 293T cell line by HEY2 polyclonal antibody. Lane 1: HEY2 transfected lysate(37.07 KDa). Lane 2: Non-transfected lysate.

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