Gene Symbol | HEY2 |
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Entrez Gene | 23493 |
Alt Symbol | CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32 |
Species | Human |
Gene Type | protein-coding |
Description | hes-related family bHLH transcription factor with YRPW motif 2 |
Other Description | HES-related repressor protein 1|HES-related repressor protein 2|HESR-2|HRT-2|cardiovascular basic helix-loop-helix factor 1|cardiovascular helix-loop-helix factor 1|class B basic helix-loop-helix protein 32|hCHF1|hHRT2|hairy and enhancer of split-related protein 2|hairy-related transcription factor 2|hairy/enhancer-of-split related with YRPW motif 2|hairy/enhancer-of-split related with YRPW motif protein 2|protein gridlock homolog |
Swissprots | Q9UBP5 |
Accessions | EAW48135 Q9UBP5 AB044755 BAA96781 AF173901 AAF20173 AF232238 AAF37296 AF237949 AAF44781 AF311884 AAG31157 AJ249545 CAB56839 AK289943 BAF82632 AK303890 BAG64825 BC007707 AAH07707 BI549391 BT020067 AAV38870 BT020068 AAV38871 XM_005266878 XP_005266935 XM_011535649 XP_011533951 XM_011535650 XP_011533952 NM_012259 NP_036391 |
Function | Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. {ECO:0000269|PubMed:10692439, ECO:0000269|PubMed:11095750, ECO:0000269|PubMed:15485867, ECO:0000269|PubMed:16293227}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}. |
Human HEY2 full length protein - ab132308 from Abcam
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Human HEY2 protein fragment - ab153231 from Abcam
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Mouse HEY2 peptide - ab38053 from Abcam
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Mouse HEY2 peptide - ab38054 from Abcam
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CHF1 / HEY2 Antibody Blocking Peptide - LS-E8041 from LifeSpan Bioscience
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CHF1 / HEY2 Antibody Blocking Peptide - LS-E27399 from LifeSpan Bioscience
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CHF1 / HEY2 Antibody Blocking Peptide - LS-E14052 from LifeSpan Bioscience
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Recombinant Human HEY2 Protein - H00023493-P01 from Novus Biologicals
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Recombinant Human HEY2 Protein - H00023493-Q01 from Novus Biologicals
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HEY2-Antibody-N-term-Blocking-peptide - BP5914a from Abgent, a WuXi AppTec company
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Goat anti HEY2 antibody Immunizing peptide - orb16964 from Biorbyt
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HEY2 Peptide - AC21-2223-P from Abcore
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HEY2 - H00023493-P01-10 from Acris Antibodies
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HEY2 - H00023493-P01-25 from Acris Antibodies
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HEY2 - H00023493-Q01-10 from Acris Antibodies
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HEY2 - H00023493-Q01-25 from Acris Antibodies
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HEY2 Peptide - 42-617P from ProSci
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HEY2 fusion protein - ag0913 from Proteintech Group
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Recombinant Human Hairy/enhancer-of-split related with YRPW motif protein 2(HEY2) - CSB-YP883365HU CSB-EP883365HU CSB-BP883365HU CSB-MP883365HU from Cusabio
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HEY2 - TP302544 from Acris Antibodies
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HEY2, Peptide - MBS427319 from MyBioSource
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HEY2 Recombinant Protein Antigen - NBP1-88629PEP from Novus Biologicals
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HEY2 Blocking Peptide - abx061242 from Abbexa
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HEY2 Peptide, Human - M34GP06962H from Creative Peptides
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HEY2 Blocking Peptide - CBP5155 from Cohesion Biosciences
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