Gene Symbol | AMIGO2 |
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Entrez Gene | 347902 |
Alt Symbol | ALI1, AMIGO-2, DEGA |
Species | Human |
Gene Type | protein-coding |
Description | adhesion molecule with Ig-like domain 2 |
Other Description | alivin 1|amphoterin induced gene 2|amphoterin-induced protein 2|differentially expressed in gastric adenocarcinoma|differentially expressed in gastric adenocarcinomas|transmembrane protein AMIGO2 |
Swissprots | Q96CN8 Q4VBP6 Q86SJ2 Q7Z4A0 |
Accessions | CCF77052 EAW57923 EAW57924 Q86SJ2 AB079074 BAC81188 AB080610 BAC81189 AK091761 BAG52413 AK093111 BAG52657 AL833007 CAH56293 AY237005 AAO48946 AY454159 AAR83271 BC014103 AAH14103 BC047595 AAH47595 BC095477 AAH95477 CN397638 XM_005268837 XP_005268894 NM_001143668 NP_001137140 NM_181847 NP_862830 |
Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons (By similarity). {ECO:0000250}. |
Tissue Specificity | Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers. {ECO:0000269|PubMed:15107827}. |
AMIGO2 (C-14) - sc-46759 from Santa Cruz Biotechnology
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AMIGO2 (C-15) - sc-46760 from Santa Cruz Biotechnology
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AMIGO2 (G-7) - sc-373699 from Santa Cruz Biotechnology
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AMIGO2 (H-44) - sc-99229 from Santa Cruz Biotechnology
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AMIGO2 (N-12) - sc-46761 from Santa Cruz Biotechnology
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Anti-AMIGO2 antibody - ab84416 from Abcam
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Anti-AMIGO2 antibody - ab84476 from Abcam
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Anti-AMIGO2 antibody [MM0656-4D27] - ab201591 from Abcam
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Anti-AMIGO2 Antibody (aa290-339) - LS-C135358 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa75-124) - LS-C201662 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (C-Terminus) IHC-plus⢠- LS-B10237 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa449-464) IHC-plus⢠- LS-B659 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465, FITC) - LS-C221420 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465, Biotin) - LS-C221419 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465, AP) - LS-C221417 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465, APC) - LS-C221418 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody - LS-C306232 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465, Azide-free, HRP) - LS-C221421 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465, PE) - LS-C221422 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa435-465) - LS-C329212 from LifeSpan Bioscience
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Anti-AMIGO2 Antibody (aa39-391, clone 290728) - LS-C346441 from LifeSpan Bioscience
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AMIGO2 Antibody (273617) - MAB2080 from Novus Biologicals
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AMIGO2 Antibody (290728) - MAB2374 from Novus Biologicals
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AMIGO2 Antibody [Unconjugated] - AF2080 from Novus Biologicals
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AMIGO2 Antibody - H00347902-B01P from Novus Biologicals
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